Alcohol Withdrawal with Delirium Tremens.

Courtney Schwebach, Amrita Vempati
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In 2016, it was the 7th leading risk factor for deaths and disability-adjusted life years globally.1 Among heavy alcohol users admitted for hospital management, the incidence of alcohol withdrawal syndrome is estimated to be 1.9 to 6.7%.1 Alcohol withdrawal (AW) in the ED has been associated with increased use of critical care resources, and frequent ED visits for alcohol-related presentations have been associated with mortality rates that are about 1-4% when withdrawal progresses to delirium tremens (DTs).1 Patients with alcohol withdrawal can present in many different ways to the ED including anxiety, tachycardia, delirium tremens (DTs), seizures and severe autonomic dysfunction leading to severe sickness and death.2 Therefore, it is extremely important for an EM physician to recognize the signs of AW in patients and to manage the critically ill patients. In addition, Clinical Institute Withdrawal Assessment (CIWA) of alcohol was developed to assess severity of alcohol withdrawal in 1989.3 EM physicians should utilize CIWA to help determine the severity of AW.</p><p><strong>Educational objectives: </strong>By the end of the session, learner will be able to 1) discuss the causes of altered mental status, 2) utilize CIWA scoring system to quantify AW severity, 3) formulate appropriate treatment plan for AW by treating with benzodiazepine and escalating treatment appropriately, 4) treat electrolyte abnormalities by giving appropriate medications for hypokalemia and hypomagnesemia, and 5) discuss clinical progression and timing to AW.</p><p><strong>Educational methods: </strong>This session was conducted using high-fidelity simulation, which was immediately followed by an in-depth debriefing session. The session was run during first year EM resident intern orientation, and it was run during two consecutive years. 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As they recognize the cause of mental status, the patient quickly decompensates into developing severe agitation and autonomic dysfunction requiring learners to manage the patient and establish an airway. 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引用次数: 0

Abstract

Audience: Emergency medicine (EM) residents (1st year and 2nd year levels), 4th year medical students and advanced practice providers.

Introduction: Alcohol use has played a major role in causing significant morbidity and mortality for patients. In 2016, it was the 7th leading risk factor for deaths and disability-adjusted life years globally.1 Among heavy alcohol users admitted for hospital management, the incidence of alcohol withdrawal syndrome is estimated to be 1.9 to 6.7%.1 Alcohol withdrawal (AW) in the ED has been associated with increased use of critical care resources, and frequent ED visits for alcohol-related presentations have been associated with mortality rates that are about 1-4% when withdrawal progresses to delirium tremens (DTs).1 Patients with alcohol withdrawal can present in many different ways to the ED including anxiety, tachycardia, delirium tremens (DTs), seizures and severe autonomic dysfunction leading to severe sickness and death.2 Therefore, it is extremely important for an EM physician to recognize the signs of AW in patients and to manage the critically ill patients. In addition, Clinical Institute Withdrawal Assessment (CIWA) of alcohol was developed to assess severity of alcohol withdrawal in 1989.3 EM physicians should utilize CIWA to help determine the severity of AW.

Educational objectives: By the end of the session, learner will be able to 1) discuss the causes of altered mental status, 2) utilize CIWA scoring system to quantify AW severity, 3) formulate appropriate treatment plan for AW by treating with benzodiazepine and escalating treatment appropriately, 4) treat electrolyte abnormalities by giving appropriate medications for hypokalemia and hypomagnesemia, and 5) discuss clinical progression and timing to AW.

Educational methods: This session was conducted using high-fidelity simulation, which was immediately followed by an in-depth debriefing session. The session was run during first year EM resident intern orientation, and it was run during two consecutive years. There was a total of 32 EM residents who participated. There was a total of 16 residents who actively managed the patient while the other 16 were observers. Each session had four learners and was run twice in two separate rooms. There was one simulation instructor running the session and one simulation technician who acted as a nurse.

Research methods: After the simulation and debriefing session was complete, an online survey was sent via surveymonkey.com to all the participants. The survey collected responses to the following questions: (1) the case was believable, (2) the case had right the amount of complexity (based on their Gestalt), (3) the case helped in improving medical knowledge and patient care, (4) the simulation environment gave me a real-life experience and, (5) the debriefing session after simulation helped improve my knowledge. The responses were collected using a Likert scale of 1 to 5 with 1 being "Strongly disagree" and 5 being "Strongly agree."

Results: There was a total of 15 respondents from both years. One hundred percent of them either agreed or strongly agreed that the case was beneficial in learning, in improving medical knowledge and in patient care. All of them found the post-session debrief to be very helpful. Two of them felt neutral about the case being realistic. The median response for questions 1, 3 and 5 is 5. The median response for questions 2 and 4 was 4. The range of responses for questions 1, 2, 3 and 5 was 4-5 while the range for question 4 was 3-5.

Discussion: This high-fidelity simulation was a cost-effective and realistic way of educating learners on how to manage AW with DTs. Learners are forced to start with a broad differential for the patient who presents with AMS. As they recognize the cause of mental status, the patient quickly decompensates into developing severe agitation and autonomic dysfunction requiring learners to manage the patient and establish an airway. Learners found the case to be beneficial in learning the management of AW.

Topics: Alcohol withdrawal, delirium tremens, agitation, altered mental status.

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酒精戒断伴震颤谵妄。
受众:急诊医学(EM)住院医师(一年级和二年级),四年级医学生和高级实践提供者。导论:酒精使用在导致患者显著发病率和死亡率方面发挥了重要作用。2016年,它是全球死亡和残疾调整生命年的第七大风险因素在接受医院管理的重度酒精使用者中,酒精戒断综合征的发生率估计为1.9%至6.7%急诊科的酒精戒断(AW)与重症监护资源的使用增加有关,当戒断进展为震颤谵妄(DTs)时,因酒精相关症状而频繁到急诊科就诊的死亡率约为1-4%酒精戒断患者可能以多种不同的方式出现在急诊科,包括焦虑、心动过速、震颤谵妄(DTs)、癫痫发作和严重的自主神经功能障碍,导致严重的疾病和死亡因此,对于急诊医师来说,识别患者的体征和管理危重患者是非常重要的。此外,1989年制定了酒精临床研究所戒断评估(CIWA)来评估酒精戒断的严重程度。3 . EM医生应利用CIWA来帮助确定AW的严重程度。教育目标:在课程结束时,学习者将能够1)讨论精神状态改变的原因,2)利用CIWA评分系统量化AW的严重程度,3)通过苯二氮卓类药物治疗和适当的升级治疗来制定适当的AW治疗计划,4)通过给予适当的低钾血症和低镁血症药物来治疗电解质异常,5)讨论AW的临床进展和时机。教育方法:本次会议采用高保真模拟进行,紧接着是深入的汇报会议。该课程在第一年的新兴市场住院实习培训中进行,并连续两年进行。共有32名EM居民参与。共有16名住院医生积极管理患者,其他16名是观察员。每节课有四名学习者,在两个独立的房间里进行两次学习。有一名模拟教练主持会议,一名模拟技术人员担任护士。研究方法:模拟和汇报结束后,通过surveymonkey.com向所有参与者发送一份在线调查。调查收集了以下问题的回答:(1)案例是否可信,(2)案例的复杂程度是否合适(基于他们的格式塔),(3)案例有助于提高医学知识和患者护理,(4)模拟环境给了我真实的体验,(5)模拟后的汇报有助于提高我的知识。问卷采用李克特量表(Likert scale)收集,从1到5分,1代表“非常不同意”,5代表“非常同意”。结果:两年度共15名被调查者。他们中百分之百的人要么同意,要么强烈同意,这个案例对学习、提高医学知识和病人护理有益。他们都认为会后的汇报很有帮助。其中两人对案例的真实性持中立态度。问题1、3和5的回答中位数是5。问题2和问题4的中位数回答是4。问题1、2、3和5的回答范围是4-5,问题4的回答范围是3-5。讨论:这种高保真仿真是教育学习者如何使用dt管理AW的一种经济有效且现实的方法。学习者被迫开始与病人谁提出了AMS广泛的区别。当他们认识到精神状态的原因时,患者迅速失代偿发展为严重的躁动和自主神经功能障碍,需要学习者管理患者并建立气道。学员认为本案例对学习AW管理有一定的帮助。主题:酒精戒断,震颤谵妄,躁动,精神状态改变。
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