Marco V José, Juan R Bobadilla, Gabriel S Zamudio, Sávio Torres de Farías
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引用次数: 0
Abstract
In this work, we formulate the following question: How the distribution of aminoacyl-tRNA synthetases (aaRSs) went from an ancestral bidirectional gene (mirror symmetry) to the symmetrical distribution of aaRSs in a six-dimensional hypercube of the Standard Genetic Code (SGC)? We assume a primeval RNY code, two Extended Genetic RNA codes type 1 and 2, and the SGC. We outline the types of symmetries of the distribution of aaRSs in each code. The symmetry groups of aaRSs in each code are described, until the symmetries of the SGC display a mirror symmetry. Considering both Extended RNA codes the 20 aaRSs were already present before the Last Universal Ancestor. These findings reveal intricacies in the diversification of aaRSs accompanied by the evolution of the genetic code.
期刊介绍：
Theory in Biosciences focuses on new concepts in theoretical biology. It also includes analytical and modelling approaches as well as philosophical and historical issues. Central topics are:
Artificial Life;
Bioinformatics with a focus on novel methods, phenomena, and interpretations;
Bioinspired Modeling;
Complexity, Robustness, and Resilience;
Embodied Cognition;
Evolutionary Biology;
Evo-Devo;
Game Theoretic Modeling;
Genetics;
History of Biology;
Language Evolution;
Mathematical Biology;
Origin of Life;
Philosophy of Biology;
Population Biology;
Systems Biology;
Theoretical Ecology;
Theoretical Molecular Biology;
Theoretical Neuroscience & Cognition.
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