{"title":"Ca2+循环缺陷与胰岛素抵抗和心力衰竭有关。","authors":"Qian Shi, Duane D Hall, Long-Sheng Song","doi":"10.1093/lifemeta/loac014","DOIUrl":null,"url":null,"abstract":"<p><p>In a recent study published in <i>Life Metabolism</i>, Quan <i>et al</i>. reported that intracellular Ca<sup>2+</sup> dysregulation in cardiomyocyte can be both a cause and an effect of cardiac insulin resistance that ultimately leads to diabetic cardiomyopathy.</p>","PeriodicalId":74074,"journal":{"name":"Life metabolism","volume":"1 1","pages":"2-3"},"PeriodicalIF":3.4000,"publicationDate":"2022-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10426325/pdf/","citationCount":"0","resultStr":"{\"title\":\"A Ca<sup>2+</sup> cycling defect connects insulin resistance and heart failure.\",\"authors\":\"Qian Shi, Duane D Hall, Long-Sheng Song\",\"doi\":\"10.1093/lifemeta/loac014\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>In a recent study published in <i>Life Metabolism</i>, Quan <i>et al</i>. reported that intracellular Ca<sup>2+</sup> dysregulation in cardiomyocyte can be both a cause and an effect of cardiac insulin resistance that ultimately leads to diabetic cardiomyopathy.</p>\",\"PeriodicalId\":74074,\"journal\":{\"name\":\"Life metabolism\",\"volume\":\"1 1\",\"pages\":\"2-3\"},\"PeriodicalIF\":3.4000,\"publicationDate\":\"2022-08-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10426325/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Life metabolism\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1093/lifemeta/loac014\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2022/8/4 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Life metabolism","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1093/lifemeta/loac014","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2022/8/4 0:00:00","PubModel":"Epub","JCR":"","JCRName":"","Score":null,"Total":0}
A Ca2+ cycling defect connects insulin resistance and heart failure.
In a recent study published in Life Metabolism, Quan et al. reported that intracellular Ca2+ dysregulation in cardiomyocyte can be both a cause and an effect of cardiac insulin resistance that ultimately leads to diabetic cardiomyopathy.
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