利培酮引起的贫血。

IF 0.4 4区 医学 Q3 MEDICINE, GENERAL & INTERNAL National Medical Journal of India Pub Date : 2023-01-01 DOI:10.25259/NMJI_115_20
Siddarthkumar Chawath, Santosh Ramdurg, Sharan Badiger, Shivakumar P Chaukimath
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引用次数: 0

摘要

利培酮是一种非典型的抗精神病药物,用于精神分裂症,也用于治疗谵妄患者的兴奋和攻击。与氯氮平等其他药物相比,利培酮的化学和药理学特征不同,因此其血液毒性风险较低。血液学异常有危及生命的并发症,尤其是中性粒细胞减少症、白细胞减少症和粒细胞缺乏症,但它们对成人红细胞的影响尚不清楚。我们强调利培酮对红细胞的影响以及导致贫血的机制。据我们所知,这是唯一一份2名患者的报告,显示了导致利培酮诱导的贫血的多种机制。
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Risperidone-induced anaemia.

Risperidone is an atypical antipsychotic drug, which is used in schizophrenia and also to treat excitation and aggression in patients with delirium. Risperidone has a low risk of haematotoxicity because of its different chemical and pharmacological profile compared to other drugs such as clozapine. Haematological abnormalities have life-threatening complications, especially neutropenia, leucopenia and agranulocytosis, but their effect on erythrocytes in adults is less well known. We highlight the effect of risperidone on erythrocytes and the mechanism that leads to anaemia. To the best of our knowledge, this is the only report of 2 patients showing combinations of mechanisms leading to risperidone-induced anaemia.

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来源期刊
National Medical Journal of India
National Medical Journal of India 医学-医学:内科
CiteScore
0.50
自引率
0.00%
发文量
171
审稿时长
>12 weeks
期刊介绍: The journal will cover technical and clinical studies related to health, ethical and social issues in field of health policy and health provider training through sections on ‘Medicine and society’ and ‘Medical education’.. Articles with clinical interest and implications will be given preference.
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