药师主导的干预措施对越南哮喘患者服药依从性的影响:一项随机对照试验。

IF 1.8 Q3 RESPIRATORY SYSTEM Advances in respiratory medicine Pub Date : 2023-06-13 DOI:10.3390/arm91030020
Tan Thanh Nguyen, Mai Thi Xuan Truong, Dung Ngoc Lam, Tuyen Thi Thanh Le, Mai Tuyet Vi, Thanh My Tran, Thu Pham Minh Vo, Suol Thanh Pham, Bao Lam Thai Tran, Thang Nguyen, Lam Van Nguyen
{"title":"药师主导的干预措施对越南哮喘患者服药依从性的影响:一项随机对照试验。","authors":"Tan Thanh Nguyen,&nbsp;Mai Thi Xuan Truong,&nbsp;Dung Ngoc Lam,&nbsp;Tuyen Thi Thanh Le,&nbsp;Mai Tuyet Vi,&nbsp;Thanh My Tran,&nbsp;Thu Pham Minh Vo,&nbsp;Suol Thanh Pham,&nbsp;Bao Lam Thai Tran,&nbsp;Thang Nguyen,&nbsp;Lam Van Nguyen","doi":"10.3390/arm91030020","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Medication adherence in asthmatic patients enhances the effectiveness of treatments, but some studies in low and middle-income countries still show some limitations. Our study aimed to determine if pharmacist-led interventions could increase medication adherence, improve treatment effectiveness, and relieve symptom severity in outpatients with asthma.</p><p><strong>Methods: </strong>We conducted a randomized, controlled trial on 247 asthmatic outpatients (aged ≥ 16) with a 1:1 ratio randomization at the hospitalization time and repeated after 1-month discharge. The primary outcome was to detect the difference in medication adherence between groups. Adherence was assessed by the general medication adherence scale (GMAS). Data collected by questionnaire was coded and entered into SPSS_20 for statistical analysis; Results: 247 patients (123 intervention, 124 control) were enrolled (61.1% male). After intervention, the adherence rate was higher among the intervention group than the control group (94.3% vs. 82.8%, <i>p</i> = 0.001). Patient behavior and knowledge were enhanced in the intervention group (<i>p</i> < 0.05). Asthma symptoms were relieved in the intervention group (<i>p</i> = 0.014). Pharmacist-led interventions on adherence rate were higher with OR: 3.550, 95% CI: 1.378-9.143, <i>p</i> = 0.009.</p><p><strong>Conclusions: </strong>pharmaceutical intervention could improve medication adherence, treatment efficacy, and the outcome should not be taken for granted; further research should be carried out in this regard.</p>","PeriodicalId":7391,"journal":{"name":"Advances in respiratory medicine","volume":null,"pages":null},"PeriodicalIF":1.8000,"publicationDate":"2023-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10295109/pdf/","citationCount":"0","resultStr":"{\"title\":\"Effect of Pharmacist-Led Interventions on Medication Adherence among Vietnamese Patients with Asthma: A Randomized Controlled Trial.\",\"authors\":\"Tan Thanh Nguyen,&nbsp;Mai Thi Xuan Truong,&nbsp;Dung Ngoc Lam,&nbsp;Tuyen Thi Thanh Le,&nbsp;Mai Tuyet Vi,&nbsp;Thanh My Tran,&nbsp;Thu Pham Minh Vo,&nbsp;Suol Thanh Pham,&nbsp;Bao Lam Thai Tran,&nbsp;Thang Nguyen,&nbsp;Lam Van Nguyen\",\"doi\":\"10.3390/arm91030020\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Medication adherence in asthmatic patients enhances the effectiveness of treatments, but some studies in low and middle-income countries still show some limitations. Our study aimed to determine if pharmacist-led interventions could increase medication adherence, improve treatment effectiveness, and relieve symptom severity in outpatients with asthma.</p><p><strong>Methods: </strong>We conducted a randomized, controlled trial on 247 asthmatic outpatients (aged ≥ 16) with a 1:1 ratio randomization at the hospitalization time and repeated after 1-month discharge. The primary outcome was to detect the difference in medication adherence between groups. Adherence was assessed by the general medication adherence scale (GMAS). Data collected by questionnaire was coded and entered into SPSS_20 for statistical analysis; Results: 247 patients (123 intervention, 124 control) were enrolled (61.1% male). After intervention, the adherence rate was higher among the intervention group than the control group (94.3% vs. 82.8%, <i>p</i> = 0.001). Patient behavior and knowledge were enhanced in the intervention group (<i>p</i> < 0.05). Asthma symptoms were relieved in the intervention group (<i>p</i> = 0.014). Pharmacist-led interventions on adherence rate were higher with OR: 3.550, 95% CI: 1.378-9.143, <i>p</i> = 0.009.</p><p><strong>Conclusions: </strong>pharmaceutical intervention could improve medication adherence, treatment efficacy, and the outcome should not be taken for granted; further research should be carried out in this regard.</p>\",\"PeriodicalId\":7391,\"journal\":{\"name\":\"Advances in respiratory medicine\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.8000,\"publicationDate\":\"2023-06-13\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10295109/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Advances in respiratory medicine\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.3390/arm91030020\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"RESPIRATORY SYSTEM\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Advances in respiratory medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3390/arm91030020","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"RESPIRATORY SYSTEM","Score":null,"Total":0}
引用次数: 0

摘要

背景:哮喘患者的药物依从性提高了治疗的有效性,但在低收入和中等收入国家的一些研究仍然显示出一些局限性。我们的研究旨在确定药剂师主导的干预措施是否可以增加哮喘门诊患者的药物依从性,提高治疗效果,缓解症状严重程度。方法:对247例年龄≥16岁的哮喘门诊患者进行随机对照试验,住院时按1:1比例随机,出院后1个月重复。主要结果是检测组间药物依从性的差异。采用一般药物依从性量表(GMAS)评估依从性。对问卷收集的数据进行编码,录入SPSS_20进行统计分析;结果:纳入247例患者(干预组123例,对照组124例),其中男性61.1%。干预后,干预组依从率高于对照组(94.3% vs. 82.8%, p = 0.001)。干预组患者的行为和知识均有所提高(p < 0.05)。干预组哮喘症状明显缓解(p = 0.014)。药师主导干预对依从率的影响较高,OR: 3.550, 95% CI: 1.378 ~ 9.143, p = 0.009。结论:药物干预可提高患者的服药依从性和治疗效果,其结果不应想当然;在这方面应进行进一步的研究。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

摘要图片

查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
Effect of Pharmacist-Led Interventions on Medication Adherence among Vietnamese Patients with Asthma: A Randomized Controlled Trial.

Background: Medication adherence in asthmatic patients enhances the effectiveness of treatments, but some studies in low and middle-income countries still show some limitations. Our study aimed to determine if pharmacist-led interventions could increase medication adherence, improve treatment effectiveness, and relieve symptom severity in outpatients with asthma.

Methods: We conducted a randomized, controlled trial on 247 asthmatic outpatients (aged ≥ 16) with a 1:1 ratio randomization at the hospitalization time and repeated after 1-month discharge. The primary outcome was to detect the difference in medication adherence between groups. Adherence was assessed by the general medication adherence scale (GMAS). Data collected by questionnaire was coded and entered into SPSS_20 for statistical analysis; Results: 247 patients (123 intervention, 124 control) were enrolled (61.1% male). After intervention, the adherence rate was higher among the intervention group than the control group (94.3% vs. 82.8%, p = 0.001). Patient behavior and knowledge were enhanced in the intervention group (p < 0.05). Asthma symptoms were relieved in the intervention group (p = 0.014). Pharmacist-led interventions on adherence rate were higher with OR: 3.550, 95% CI: 1.378-9.143, p = 0.009.

Conclusions: pharmaceutical intervention could improve medication adherence, treatment efficacy, and the outcome should not be taken for granted; further research should be carried out in this regard.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Advances in respiratory medicine
Advances in respiratory medicine RESPIRATORY SYSTEM-
CiteScore
2.60
自引率
0.00%
发文量
90
期刊介绍: "Advances in Respiratory Medicine" is a new international title for "Pneumonologia i Alergologia Polska", edited bimonthly and addressed to respiratory professionals. The Journal contains peer-reviewed original research papers, short communications, case-reports, recommendations of the Polish Respiratory Society concerning the diagnosis and treatment of lung diseases, editorials, postgraduate education articles, letters and book reviews in the field of pneumonology, allergology, oncology, immunology and infectious diseases. "Advances in Respiratory Medicine" is an open access, official journal of Polish Society of Lung Diseases, Polish Society of Allergology and National Research Institute of Tuberculosis and Lung Diseases.
期刊最新文献
Expression of Epithelial Alarmin Receptor on Innate Lymphoid Cells Type 2 in Eosinophilic Chronic Obstructive Pulmonary Disease. Utility of Raman Spectroscopy in Pulmonary Medicine. Secure and Transparent Lung and Colon Cancer Classification Using Blockchain and Microsoft Azure. Comparing the Effects of Two Surfactant Administration Methods: Minimally Invasive Surfactant Therapy (MIST) with Intubation (INSURE) in Infants with Respiratory Distress Syndrome. The Impact of Different Telerehabilitation Methods on Peripheral Muscle Strength and Aerobic Capacity in COPD Patients: A Randomized Controlled Trial.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1