{"title":"二次牙槽骨移植对唇腭裂患者上颌骨生长的影响：系统回顾与元分析","authors":"Phavithrasri Kannan, Sanjeev Verma, Vinay Kumar, Raj Kumar Verma, Satinder Pal Singh","doi":"10.1177/10556656231188600","DOIUrl":null,"url":null,"abstract":"<p><p>To assess the effect of secondary alveolar bone grafting (SABG) on maxillary growth in patients with unilateral cleft lip or palate (UCL/P).</p><p><p>Systematic review and Meta-analysis.</p><p><p>Pubmed, Cochrane Library, Embase, Scopus, Web of Science and manual search was performed to assess the maxillary growth following SABG in UCL/P patients.</p><p><p>Non-syndromic patients with UCL/P.</p><p><p>Comparison of maxillary growth between patients with UCL/P who underwent SABG and UCL/P patients who had not undergone SABG or non-cleft control.</p><p><p>39 of the identified 233 articles were assessed for inclusion and exclusion criteria after duplicate removal and title and abstract reading. 7 articles (1 prospective, and 6 retrospective studies) were included in the qualitative analysis and 2 articles were subjected to quantitative analysis. Four studies had a low risk of bias and three studies had a moderate risk of bias. Meta-analysis revealed a significant reduction of SNA and no significant difference in ANB in the SABG group compared to the non-cleft control group(I<sup>2 </sup>= 0%). There was no significant difference in ANB between SABG and non-cleft control; however, results showed high heterogeneity(I<sup>2 </sup>= 83%). Meta-analysis of SNA and ANB showed no significant difference between SABG and the cleft control group; however, there was high heterogeneity.</p><p><p>The studies showed a low to moderate risk of bias. SABG causes inhibition of maxillary growth in patients with cleft lip or palate when compared to patients with non-cleft control. Due to high heterogeneity, comparison to cleft control showed insufficient evidence.</p>","PeriodicalId":55255,"journal":{"name":"Cleft Palate-Craniofacial Journal","volume":" ","pages":"1860-1872"},"PeriodicalIF":1.2000,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Effects of Secondary Alveolar Bone Grafting on Maxillary Growth in Cleft Lip or Palate Patients: A Systematic Review and Meta-Analysis.\",\"authors\":\"Phavithrasri Kannan, Sanjeev Verma, Vinay Kumar, Raj Kumar Verma, Satinder Pal Singh\",\"doi\":\"10.1177/10556656231188600\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>To assess the effect of secondary alveolar bone grafting (SABG) on maxillary growth in patients with unilateral cleft lip or palate (UCL/P).</p><p><p>Systematic review and Meta-analysis.</p><p><p>Pubmed, Cochrane Library, Embase, Scopus, Web of Science and manual search was performed to assess the maxillary growth following SABG in UCL/P patients.</p><p><p>Non-syndromic patients with UCL/P.</p><p><p>Comparison of maxillary growth between patients with UCL/P who underwent SABG and UCL/P patients who had not undergone SABG or non-cleft control.</p><p><p>39 of the identified 233 articles were assessed for inclusion and exclusion criteria after duplicate removal and title and abstract reading. 7 articles (1 prospective, and 6 retrospective studies) were included in the qualitative analysis and 2 articles were subjected to quantitative analysis. Four studies had a low risk of bias and three studies had a moderate risk of bias. Meta-analysis revealed a significant reduction of SNA and no significant difference in ANB in the SABG group compared to the non-cleft control group(I<sup>2 </sup>= 0%). There was no significant difference in ANB between SABG and non-cleft control; however, results showed high heterogeneity(I<sup>2 </sup>= 83%). Meta-analysis of SNA and ANB showed no significant difference between SABG and the cleft control group; however, there was high heterogeneity.</p><p><p>The studies showed a low to moderate risk of bias. SABG causes inhibition of maxillary growth in patients with cleft lip or palate when compared to patients with non-cleft control. 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引用次数: 0
摘要
系统综述和 Meta 分析.Pubmed、Cochrane 图书馆、Embase、Scopus、Web of Science 和人工搜索评估了单侧唇腭裂（UCL/P）患者接受 SABG 后的上颌骨生长情况。对接受SABG手术的UCL/P患者与未接受SABG手术或非左侧对照的UCL/P患者的上颌骨生长情况进行了比较。在删除重复文章、阅读标题和摘要后，对已确定的 233 篇文章进行了纳入和排除标准评估。定性分析包括 7 篇文章（1 篇前瞻性研究和 6 篇回顾性研究），定量分析包括 2 篇文章。四项研究存在低度偏倚风险，三项研究存在中度偏倚风险。Meta 分析显示，与非左侧对照组相比，SABG 组的 SNA 显著降低，而 ANB 无显著差异（I2 = 0%）。SABG 组和非左撇子对照组的 ANB 无明显差异；但结果显示异质性很高（I2 = 83%）。对 SNA 和 ANB 的 Meta 分析表明，SABG 与裂隙对照组之间无明显差异，但存在高度异质性。与非唇裂对照组患者相比，SABG 会抑制唇裂或腭裂患者的上颌骨生长。由于存在高度异质性，与唇裂对照组相比证据不足。
Effects of Secondary Alveolar Bone Grafting on Maxillary Growth in Cleft Lip or Palate Patients: A Systematic Review and Meta-Analysis.
To assess the effect of secondary alveolar bone grafting (SABG) on maxillary growth in patients with unilateral cleft lip or palate (UCL/P).
Systematic review and Meta-analysis.
Pubmed, Cochrane Library, Embase, Scopus, Web of Science and manual search was performed to assess the maxillary growth following SABG in UCL/P patients.
Non-syndromic patients with UCL/P.
Comparison of maxillary growth between patients with UCL/P who underwent SABG and UCL/P patients who had not undergone SABG or non-cleft control.
39 of the identified 233 articles were assessed for inclusion and exclusion criteria after duplicate removal and title and abstract reading. 7 articles (1 prospective, and 6 retrospective studies) were included in the qualitative analysis and 2 articles were subjected to quantitative analysis. Four studies had a low risk of bias and three studies had a moderate risk of bias. Meta-analysis revealed a significant reduction of SNA and no significant difference in ANB in the SABG group compared to the non-cleft control group(I2 = 0%). There was no significant difference in ANB between SABG and non-cleft control; however, results showed high heterogeneity(I2 = 83%). Meta-analysis of SNA and ANB showed no significant difference between SABG and the cleft control group; however, there was high heterogeneity.
The studies showed a low to moderate risk of bias. SABG causes inhibition of maxillary growth in patients with cleft lip or palate when compared to patients with non-cleft control. Due to high heterogeneity, comparison to cleft control showed insufficient evidence.
期刊介绍：
The Cleft Palate-Craniofacial Journal (CPCJ) is the premiere peer-reviewed, interdisciplinary, international journal dedicated to current research on etiology, prevention, diagnosis, and treatment in all areas pertaining to craniofacial anomalies. CPCJ reports on basic science and clinical research aimed at better elucidating the pathogenesis, pathology, and optimal methods of treatment of cleft and craniofacial anomalies. The journal strives to foster communication and cooperation among professionals from all specialties.
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