少钠、多钾或两者兼有:预防高血压的全民策略。

IF 3.7 2区 医学 Q1 PHYSIOLOGY American Journal of Physiology-renal Physiology Pub Date : 2023-07-01 Epub Date: 2023-06-01 DOI:10.1152/ajprenal.00007.2023
Voravech Nissaisorakarn, George Ormseth, William Earle, Martha Catalina Morales-Alvarez, Swapnil Hiremath, Stephen P Juraschek
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引用次数: 0

摘要

高血压是全球发病率最高的疾病之一,也是慢性肾病、心血管疾病和死亡的主要诱因。要遏制这一世界性流行病,亟需通过非药物的人群干预措施进行预防。然而,在公共政策工作的重点方面一直存在分歧。最近,"代盐与中风研究 "证明,用钾盐代替食盐可以有效降低中风、主要心血管事件和死亡的风险。然而,这引发了关于在食盐替代不太可行的国家应优先考虑钠盐还是钾盐的争论。在本评论中,我们总结了支持减少钠摄入量或增加钾摄入量这两种策略的论点。此外,我们还讨论了与这两种策略相关的证据和政策方法,或与文化背景相关的综合方法。归根结底,迫切需要同时减少钠和增加钾摄入量的政策;然而,确定一种适合文化背景的策略将是改善全民血压的关键。
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Less sodium, more potassium, or both: population-wide strategies to prevent hypertension.

Hypertension is among the most prevalent medical conditions globally and a major contributor to chronic kidney disease, cardiovascular disease, and death. Prevention through nonpharmacological, population-level interventions is critically needed to halt this worldwide epidemic. However, there are ongoing disagreements as to where public policy efforts should focus. Recently the Salt Substitute and Stroke Study demonstrated the efficacy of substituting table salt with potassium salt to reduce the risk of stroke, major cardiovascular events, and death. However, this sparked debate over whether sodium or potassium should be prioritized in countries where table salt substitution was less feasible. In this commentary, we summarize arguments in favor of either strategy: reduced sodium or increased potassium intake. Moreover, we discuss evidence and policy approaches related to either or combined approaches relevant to cultural context. Ultimately, there is an urgent need for policies that both reduce sodium and increase potassium intake; however, identifying a strategy that fits cultural context will be key to improve population-wide blood pressures.

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来源期刊
CiteScore
8.40
自引率
7.10%
发文量
154
审稿时长
2-4 weeks
期刊介绍: The American Journal of Physiology - Renal Physiology publishes original manuscripts on timely topics in both basic science and clinical research. Published articles address a broad range of subjects relating to the kidney and urinary tract, and may involve human or animal models, individual cell types, and isolated membrane systems. Also covered are the pathophysiological basis of renal disease processes, regulation of body fluids, and clinical research that provides mechanistic insights. Studies of renal function may be conducted using a wide range of approaches, such as biochemistry, immunology, genetics, mathematical modeling, molecular biology, as well as physiological and clinical methodologies.
期刊最新文献
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