高原移民高原红细胞增多症和高尿酸血症的患病率及高尿酸血症的危险因素。

IF 1.6 4区 医学 Q4 BIOPHYSICS High altitude medicine & biology Pub Date : 2023-06-01 DOI:10.1089/ham.2022.0133
Zhen Song, Anxin Zhang, Jie Luo, Guanghai Xiong, Haibo Peng, Rang Zhou, Yuanfeng Li, Hongqiang Xu, Zhen Li, Wei Zhao, Haoxiang Zhang
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引用次数: 2

摘要

郑松,张安新,罗杰,熊广海,彭海波,周让,李元峰,徐宏强,李震,赵伟,张浩翔。高原移民高原红细胞增多症和高尿酸血症的患病率及高尿酸血症的危险因素中国生物医学工程学报,24(2):444 - 444。背景:高原移民慢性高山病(CMS)流行病学研究较少。本研究评估了高原移民中红细胞增多症和高尿酸血症(HUA)的患病率及HUA的危险因素。方法:对2021年1月至12月在青藏高原生活的7,070名15-45岁的移民进行横断面研究。从每个参与者的常规体检中获得信息。采用二元logistic回归分析确定HUA的几个危险因素之间的相关性。结果:高原红细胞增多症(HAPC)患病率为25.8%(男性28.7%,女性9.4%),HUA患病率为54.2%(男性59.9%,女性22.5%)。HAPC患病率最高的男性和女性分别是26-30岁和21-25岁的参与者。在26-30岁的参与者中,男性和女性的HUA患病率最高。二元logistic回归分析显示,年龄、性别和血红蛋白(Hb)浓度是HUA的危险因素,其中年龄为负因素,男性性别和Hb浓度为正因素。结论:移民易患HAPC和HUA。移民CMS的高发可能与Hb浓度、年龄和性别有关。
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Prevalence of High-Altitude Polycythemia and Hyperuricemia and Risk Factors for Hyperuricemia in High-Altitude Immigrants.

Song Zhen, Anxin Zhang, Jie Luo, Guanghai Xiong, Haibo Peng, Rang Zhou, Yuanfeng Li, Hongqiang Xu, Zhen Li, Wei Zhao, and Haoxiang Zhang. Prevalence of high-altitude polycythemia and hyperuricemia and risk factors for hyperuricemia in high-altitude immigrants. High Alt Med Biol. 24:132-138, 2023. Background: Few studies have investigated the epidemiology of chronic mountain sickness (CMS) in high-altitude immigrants. This study evaluated the prevalence of polycythemia and hyperuricemia (HUA) and risk factors for HUA in high-altitude immigrants. Methods: A cross-sectional study was conducted with 7,070 immigrants 15-45 years of age living on the Tibetan Plateau between January and December 2021. Information from routine physical examinations was obtained from each participant. Binary logistic regression analysis was performed to determine the correlation of several risk factors for HUA. Results: The prevalence of high-altitude polycythemia (HAPC) and HUA was 25.8% (28.7% in males and 9.4% in females) and 54.2% (59.9% in males and 22.5% in females), respectively. The highest prevalence of HAPC in males and females was observed in participants 26-30 and 21-25 years of age, respectively. The highest prevalence of HUA in both males and females was observed in participants 26-30 years of age. Binary logistic regression analysis showed that age, sex, and hemoglobin (Hb) concentration were risk factors for HUA, among which age was a negative factor and male sex and Hb concentration were positive factors. Conclusions: Immigrants are more susceptible to HAPC and HUA. The high prevalence of CMS of immigrants may be associated with Hb concentration, age, and sex.

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来源期刊
High altitude medicine & biology
High altitude medicine & biology 医学-公共卫生、环境卫生与职业卫生
CiteScore
3.80
自引率
9.50%
发文量
44
审稿时长
>12 weeks
期刊介绍: High Altitude Medicine & Biology is the only peer-reviewed journal covering the medical and biological issues that impact human life at high altitudes. The Journal delivers critical findings on the impact of high altitude on lung and heart disease, appetite and weight loss, pulmonary and cerebral edema, hypertension, dehydration, infertility, and other diseases. It covers the full spectrum of high altitude life sciences from pathology to human and animal ecology.
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