特发性多中心Castleman病综合诊断的专家共识

Q4 Medicine Revista Espanola de Patologia Pub Date : 2023-07-01 DOI:10.1016/j.patol.2022.12.003

Santiago Montes-Moreno , Fina Climent , Máximo Fraga , José Luis Patier , Ángel Robles-Marhuenda , Ramón García-Sanz , Enrique M. Ocio , Andrés González García , José-Tomás Navarro

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摘要

特发性多中心Castleman病（iMCD）是罕见的。鉴别诊断包括炎症性、自身免疫性和肿瘤性疾病。淋巴结中Castleman病的组织病理学特征的识别是主要的诊断标准。来自三个医学会（SEMI、SEHH和SEAP）的五十三名专家创建了一份多学科共识文件，以标准化Castleman病的诊断。使用德尔菲方法，为iMCD的综合诊断以及获取样本以进行组织病理学确认、正确的实验室程序以及结果解释和报告的最佳方式，提出了初步临床、实验室和影像学研究的具体建议。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Expert consensus on the integrated diagnosis of idiopathic multicentric Castleman disease

Idiopathic multicentric Castleman disease (iMCD) is rare. The differential diagnosis includes inflammatory, autoimmune and neoplastic disease. The identification of the histopathological features of Castleman disease in the lymph node is the main diagnostic criterion.

Fifty-three experts from three medical societies (SEMI, SEHH and SEAP) have created a multi-disciplinary consensus document in order to standardise the diagnosis of Castleman disease. Using the Delphi method, specific recommendations for the initial clinical, laboratory and imaging studies have been made for an integrated diagnosis of iMCD as well as for the best way to obtain samples for histopathological confirmation, correct laboratory procedure and interpretation and reporting of results.

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