Chitra S. Krishnan, Geoffrey R. Tompkins, Karl M. Lyons, Richard D. Cannon
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Database searches (Google Scholar, PubMed, Web of Science, Ovid, Scopus and Science Direct) were undertaken using MESH terms and Boolean operators with no date restrictions, to identify full-text, original reports published in English-language peer-reviewed journals.</p>\n </section>\n \n <section>\n \n <h3> Results</h3>\n \n <p>The search yielded 114 papers that met the inclusion/exclusion criteria. Dental applications of EOW include its use as an endodontic irrigant (39%); mouth rinse/surgical irrigant (21%); disinfectant for dental unit water lines (19%) and dental biomaterials (17%); and for antimicrobial efficacy, effects on oral tissues and on dental material properties. Most studies (83%) evaluated a single EOW formulation (acidic, moderately acidic or neutral) that was either generated at ‘point-of-use’ (POU; 72%), bottled (‘ready-to-use’, RTU; 24%) or from unspecified (3%) sources. Six reports evaluated storage-related parameters and 25 evaluated clinical applications; 89 were in vitro studies and one investigated the cost-effectiveness of POU EOW.</p>\n </section>\n \n <section>\n \n <h3> Conclusions</h3>\n \n <p>Neutral-pH, EOW is effective as an antimicrobial agent without deleterious effects on oral tissues. 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引用次数: 0
摘要
目的:本综述的目的是绘制电解氧化水(EOW)作为与老年人牙科应用相关的杀菌剂的证据，并确定研究空白。背景:EOW是一种新兴的“绿色”、高性价比的杀菌剂。目前还没有关于EOW作为牙科保健中的防腐剂或消毒剂或其对老年人口腔保健的适用性的研究综述。材料和方法:审查遵循PRISMA范围审查扩展(PRISMA- scr)指南。数据库检索(b谷歌Scholar, PubMed, Web of Science, Ovid, Scopus和Science Direct)使用MESH术语和布尔运算符进行，没有日期限制，以识别发表在英文同行评审期刊上的全文原创报告。结果:检索出114篇符合纳入/排除标准的论文。EOW的牙科应用包括用作牙髓冲洗剂(39%);漱口水/手术冲洗液(21%);牙科单位水管消毒剂(19%)和牙科生物材料消毒剂(17%);对于抗菌效果，对口腔组织和牙科材料性能的影响。大多数研究(83%)评估了单一EOW制剂(酸性、中酸性或中性)，这些制剂要么在“使用点”(POU)产生;72%)，瓶装(“即食”，RTU;24%)或来源不明(3%)。6份报告评估了储存相关参数，25份报告评估了临床应用;89项是体外研究，一项是研究POU - EOW的成本效益。结论:EOW为中性ph，是一种有效的抗菌药物，对口腔组织无不良影响。然而，需要对储存条件的影响、抗念珠菌生物膜的功效和对酵母的作用机制、对义齿材料的长期影响和成本效益进行研究，以确定EOW作为牙科保健的多用途杀菌剂的适用性，包括与老年人有关的感染控制要求。
Electrolysed oxidising water as a multi-purpose biocide in dental healthcare—A scoping review
Objectives
The objective of this scoping review was to map evidence of electrolysed oxidising water (EOW) as a biocide for dental applications of relevance to older people and identify research gaps.
Background
EOW is an emerging, “green,” and cost-effective biocide. There are no reviews on the landscape of EOW research as either an antiseptic or disinfectant in dental healthcare or its suitability for the oral healthcare of older people.
Materials and Methods
The review follows the PRISMA Extension for Scoping Reviews (PRISMA-ScR) guidelines. Database searches (Google Scholar, PubMed, Web of Science, Ovid, Scopus and Science Direct) were undertaken using MESH terms and Boolean operators with no date restrictions, to identify full-text, original reports published in English-language peer-reviewed journals.
Results
The search yielded 114 papers that met the inclusion/exclusion criteria. Dental applications of EOW include its use as an endodontic irrigant (39%); mouth rinse/surgical irrigant (21%); disinfectant for dental unit water lines (19%) and dental biomaterials (17%); and for antimicrobial efficacy, effects on oral tissues and on dental material properties. Most studies (83%) evaluated a single EOW formulation (acidic, moderately acidic or neutral) that was either generated at ‘point-of-use’ (POU; 72%), bottled (‘ready-to-use’, RTU; 24%) or from unspecified (3%) sources. Six reports evaluated storage-related parameters and 25 evaluated clinical applications; 89 were in vitro studies and one investigated the cost-effectiveness of POU EOW.
Conclusions
Neutral-pH, EOW is effective as an antimicrobial agent without deleterious effects on oral tissues. However, research on the impact of storage conditions, anti-Candida biofilm efficacy and mechanism of action against yeasts, long-term effects on denture materials and cost-effectiveness is required to establish the suitability of EOW as a multipurpose biocide for dental healthcare, including infection-control requirements relating to older people.
期刊介绍：
The ultimate aim of Gerodontology is to improve the quality of life and oral health of older people. The boundaries of most conventional dental specialties must be repeatedly crossed to provide optimal dental care for older people. In addition, management of other health problems impacts on dental care and clinicians need knowledge in these numerous overlapping areas. Bringing together these diverse topics within one journal serves clinicians who are seeking to read and to publish papers across a broad spectrum of specialties. This journal provides the juxtaposition of papers from traditional specialties but which share this patient-centred interest, providing a synergy that serves progress in the subject of gerodontology.
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