Emmanuel Ekanem MBBCh, FWACS, MRCOG, MRCPI, MSc (Consultant Obstetrician and Gynaecologist) , Nnabuike Chibuoke Ngene MB BS, Dip Obst (SA), Dip HIV Man (SA), MMed (Fam Med), FCOG (SA), MMmed (O&G), PhD , Jagidesa Moodley MB ChB, FCOG (SA), FRCOG, MD (Emeritus Professor) , Justin Konje MD, MBA, FMCOG, FWACS, FRCOG (Senior Consultant Obstetrician and Gynaecologist, Professor of Obstetrics and Gynecology, Emeritus Professor of Obstetrics and Gynaecology)
{"title":"预防妊娠期肥胖妇女手术部位感染和败血症","authors":"Emmanuel Ekanem MBBCh, FWACS, MRCOG, MRCPI, MSc (Consultant Obstetrician and Gynaecologist) , Nnabuike Chibuoke Ngene MB BS, Dip Obst (SA), Dip HIV Man (SA), MMed (Fam Med), FCOG (SA), MMmed (O&G), PhD , Jagidesa Moodley MB ChB, FCOG (SA), FRCOG, MD (Emeritus Professor) , Justin Konje MD, MBA, FMCOG, FWACS, FRCOG (Senior Consultant Obstetrician and Gynaecologist, Professor of Obstetrics and Gynecology, Emeritus Professor of Obstetrics and Gynaecology)","doi":"10.1016/j.bpobgyn.2023.102406","DOIUrl":null,"url":null,"abstract":"<div><p><span><span>Obesity is a major determinant of health outcomes and is on the increase in women worldwide. It predisposes to </span>surgical site infection<span> (SSI). Risk factors for the SSI include extremes of age, smoking, comorbidities such as hypertension and diabetes, inappropriate vertical abdominal and or uterine wall incisions, increased operating time, subcutaneous layer of 3 cm or more, and unnecessary use of subcutaneous drain. Most bacteria that cause SSIs are human commensals. Common organisms responsible for SSI include </span></span><span><em>Staphylococcus aureus</em></span> and coliforms such as <span><em>Proteus mirabilis</em></span>, and <em>Escherichia coli</em><span><span><span>. A surgeon's gloves post caesarean section in the obese has a preponderance of </span>Firmicutes and </span>Bacteroidetes<span>, which increases SSI risk. The interaction of skin commensals and vaginal microbiome<span> at the surgical incision<span> site increases the risk of SSI in the obese compared to non-obese. Minimizing the risk of SSI involves modification of risk factors, timely treatment of SSI to prevent sepsis and compliance with the recommended care bundles.</span></span></span></span></p></div>","PeriodicalId":50732,"journal":{"name":"Best Practice & Research Clinical Obstetrics & Gynaecology","volume":null,"pages":null},"PeriodicalIF":3.9000,"publicationDate":"2023-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":"{\"title\":\"Prevention of surgical site infection and sepsis in pregnant obese women\",\"authors\":\"Emmanuel Ekanem MBBCh, FWACS, MRCOG, MRCPI, MSc (Consultant Obstetrician and Gynaecologist) , Nnabuike Chibuoke Ngene MB BS, Dip Obst (SA), Dip HIV Man (SA), MMed (Fam Med), FCOG (SA), MMmed (O&G), PhD , Jagidesa Moodley MB ChB, FCOG (SA), FRCOG, MD (Emeritus Professor) , Justin Konje MD, MBA, FMCOG, FWACS, FRCOG (Senior Consultant Obstetrician and Gynaecologist, Professor of Obstetrics and Gynecology, Emeritus Professor of Obstetrics and Gynaecology)\",\"doi\":\"10.1016/j.bpobgyn.2023.102406\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p><span><span>Obesity is a major determinant of health outcomes and is on the increase in women worldwide. It predisposes to </span>surgical site infection<span> (SSI). Risk factors for the SSI include extremes of age, smoking, comorbidities such as hypertension and diabetes, inappropriate vertical abdominal and or uterine wall incisions, increased operating time, subcutaneous layer of 3 cm or more, and unnecessary use of subcutaneous drain. Most bacteria that cause SSIs are human commensals. Common organisms responsible for SSI include </span></span><span><em>Staphylococcus aureus</em></span> and coliforms such as <span><em>Proteus mirabilis</em></span>, and <em>Escherichia coli</em><span><span><span>. A surgeon's gloves post caesarean section in the obese has a preponderance of </span>Firmicutes and </span>Bacteroidetes<span>, which increases SSI risk. The interaction of skin commensals and vaginal microbiome<span> at the surgical incision<span> site increases the risk of SSI in the obese compared to non-obese. Minimizing the risk of SSI involves modification of risk factors, timely treatment of SSI to prevent sepsis and compliance with the recommended care bundles.</span></span></span></span></p></div>\",\"PeriodicalId\":50732,\"journal\":{\"name\":\"Best Practice & Research Clinical Obstetrics & Gynaecology\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":3.9000,\"publicationDate\":\"2023-08-19\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"2\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Best Practice & Research Clinical Obstetrics & Gynaecology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S1521693423001141\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"OBSTETRICS & GYNECOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Best Practice & Research Clinical Obstetrics & Gynaecology","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1521693423001141","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"OBSTETRICS & GYNECOLOGY","Score":null,"Total":0}
Prevention of surgical site infection and sepsis in pregnant obese women
Obesity is a major determinant of health outcomes and is on the increase in women worldwide. It predisposes to surgical site infection (SSI). Risk factors for the SSI include extremes of age, smoking, comorbidities such as hypertension and diabetes, inappropriate vertical abdominal and or uterine wall incisions, increased operating time, subcutaneous layer of 3 cm or more, and unnecessary use of subcutaneous drain. Most bacteria that cause SSIs are human commensals. Common organisms responsible for SSI include Staphylococcus aureus and coliforms such as Proteus mirabilis, and Escherichia coli. A surgeon's gloves post caesarean section in the obese has a preponderance of Firmicutes and Bacteroidetes, which increases SSI risk. The interaction of skin commensals and vaginal microbiome at the surgical incision site increases the risk of SSI in the obese compared to non-obese. Minimizing the risk of SSI involves modification of risk factors, timely treatment of SSI to prevent sepsis and compliance with the recommended care bundles.
期刊介绍:
In practical paperback format, each 200 page topic-based issue of Best Practice & Research Clinical Obstetrics & Gynaecology will provide a comprehensive review of current clinical practice and thinking within the specialties of obstetrics and gynaecology.
All chapters take the form of practical, evidence-based reviews that seek to address key clinical issues of diagnosis, treatment and patient management.
Each issue follows a problem-orientated approach that focuses on the key questions to be addressed, clearly defining what is known and not known. Management will be described in practical terms so that it can be applied to the individual patient.