治疗儿童不受控制的严重哮喘的生物药物。

IF 1.3 Q3 PEDIATRICS Current Pediatric Reviews Pub Date : 2024-01-01 DOI:10.2174/1573396320666230912103115
Cristiana Indolfi, Angela Klain, Chiara Lucia Bencivenga, Elisabetta D'Addio, Giulio Dinardo, Alberto Decimo, Michele Miraglia Del Giudice
{"title":"治疗儿童不受控制的严重哮喘的生物药物。","authors":"Cristiana Indolfi, Angela Klain, Chiara Lucia Bencivenga, Elisabetta D'Addio, Giulio Dinardo, Alberto Decimo, Michele Miraglia Del Giudice","doi":"10.2174/1573396320666230912103115","DOIUrl":null,"url":null,"abstract":"<p><p>The introduction of biological drugs for the treatment of severe allergic asthma in children, almost twenty years ago, had a substantial impact on both the pathology's clinical course and the quality of life of the patients who receive treatment. Over the years, several molecules have been developed that inhibit molecular targets involved in the pathogenesis of the asthmatic disease. Biological drugs demonstrate a significant improvement in several key clinical parameters in patients with severe asthma. In this review, we provide a concise summary of the evidence on biological therapy for children and adolescents with severe asthma.</p>","PeriodicalId":11175,"journal":{"name":"Current Pediatric Reviews","volume":" ","pages":"265-270"},"PeriodicalIF":1.3000,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Biological Drugs for the Treatment of Uncontrolled Severe Asthma in Children.\",\"authors\":\"Cristiana Indolfi, Angela Klain, Chiara Lucia Bencivenga, Elisabetta D'Addio, Giulio Dinardo, Alberto Decimo, Michele Miraglia Del Giudice\",\"doi\":\"10.2174/1573396320666230912103115\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>The introduction of biological drugs for the treatment of severe allergic asthma in children, almost twenty years ago, had a substantial impact on both the pathology's clinical course and the quality of life of the patients who receive treatment. Over the years, several molecules have been developed that inhibit molecular targets involved in the pathogenesis of the asthmatic disease. Biological drugs demonstrate a significant improvement in several key clinical parameters in patients with severe asthma. In this review, we provide a concise summary of the evidence on biological therapy for children and adolescents with severe asthma.</p>\",\"PeriodicalId\":11175,\"journal\":{\"name\":\"Current Pediatric Reviews\",\"volume\":\" \",\"pages\":\"265-270\"},\"PeriodicalIF\":1.3000,\"publicationDate\":\"2024-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Current Pediatric Reviews\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.2174/1573396320666230912103115\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"PEDIATRICS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current Pediatric Reviews","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2174/1573396320666230912103115","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"PEDIATRICS","Score":null,"Total":0}
引用次数: 0

摘要

近二十年前,用于治疗儿童严重过敏性哮喘的生物药物问世,对这一病症的临床过程和接受治疗的患者的生活质量都产生了重大影响。多年来,已开发出多种抑制哮喘发病机制分子靶点的分子。生物药物可显著改善重症哮喘患者的几项关键临床指标。在这篇综述中,我们简要总结了对患有严重哮喘的儿童和青少年进行生物治疗的证据。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
Biological Drugs for the Treatment of Uncontrolled Severe Asthma in Children.

The introduction of biological drugs for the treatment of severe allergic asthma in children, almost twenty years ago, had a substantial impact on both the pathology's clinical course and the quality of life of the patients who receive treatment. Over the years, several molecules have been developed that inhibit molecular targets involved in the pathogenesis of the asthmatic disease. Biological drugs demonstrate a significant improvement in several key clinical parameters in patients with severe asthma. In this review, we provide a concise summary of the evidence on biological therapy for children and adolescents with severe asthma.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
CiteScore
4.30
自引率
0.00%
发文量
66
期刊介绍: Current Pediatric Reviews publishes frontier reviews on all the latest advances in pediatric medicine. The journal’s aim is to publish the highest quality review articles dedicated to clinical research in the field. The journal is essential reading for all researchers and clinicians in pediatric medicine.
期刊最新文献
The Role of Newborn Pulse Oximetry Screening for Detecting Critical Congenital Heart Defects: A Narrative Review. Cardiology Consult for the General Pediatrician after Cardiac Manifestations from a SARS-CoV-2 Infection. Necrotizing Enterocolitis: A Current Understanding and Challenges for the Future. Practical Way to Use Supraglottic Airway Device. A Quantitative Review of Un-licensed and Off-label Medicines Use in Children Aged 0-2 Years in the Private Sector in South Africa: Extent, Challenges, and Implications.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1