单次体外冲击波碎石治疗10 - 20毫米单颗肾结石后结石清除率的预测因素:一项私人中心经验。

IF 0.9 4区 医学 Q4 UROLOGY & NEPHROLOGY Current Urology Pub Date : 2023-03-01 DOI:10.1097/CU9.0000000000000152
Amr A Faddan, Osama Najieb, Rabea A Gadelkareem
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引用次数: 0

摘要

背景:尽管肾结石治疗指南不断更新,但预测体外冲击波碎石(SWL)成功反应的能力仍然是一个研究课题。这是因为需要在技术进步和当前流行病的背景下改进决策。本研究旨在确定单个肾结石直径为10 - 20mm的成人患者单次SWL后无结石率(SFR)的预测因素。材料和方法:回顾性分析2019年12月至2021年2月在一家私人SWL中心进行的单个肾结石10至20mm患者的记录。对结石和患者相关因素进行单因素和多因素分析,对定量变量使用Student t检验和Mann-Whitney U检验,对定性变量使用Fisher精确检验和Pearson相关检验。结果:共有138例患者符合本研究的条件,其中男性92例,女性46例。平均年龄38.6±12.4岁,平均体重指数(BMI) 25.9±3.4 kg/m2。SWL术后4周,120例(87%)患者无结石,18例(13%)患者需要进一步治疗。单因素分析显示,SFR与BMI增加(p = 0.0001)、最大结石长度(p = 0.0001)、结石横向直径(p = 0.0001)、每次电击次数(p = 0.052)和Hounsfield单位(p = 0.0001)呈负相关。多因素分析显示,HU (p = 0.009)、最大结石长度(p = 0.01)、BMI (p = 0.000)、双j型支架的存在(p = 0.034)是单次SWL治疗直径10 ~ 20mm肾结石失败的独立危险因素。估计每箱平均费用为450.5美元。结论:HU升高、最大结石长度、BMI和双j型支架的存在是肾结石直径10 - 20mm单次SWL后低SFR的独立危险因素。在私营部门,SWL的成本仍然是一个优势。
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Predictors of stone-free rate after a single-session extracorporeal shockwave lithotripsy for a single kidney stone measuring 10 to 20 mm: A private center experience.

Background: Despite the continuous update of guidelines for the management of kidney stones, the ability to predict a successful response to extracorporeal shockwave lithotripsy (SWL) remains a topic of research. This is due to the need to refine the decision making in the context of technological advancements and current pandemics. This study aimed to determine the predictors of stone-free rate (SFR) after single-session SWL in adult patients with a single kidney stone 10 to 20 mm in diameter.

Materials and methods: A retrospective review of the records of patients with a single kidney stone 10 to 20 mm in diameter was performed at a private SWL center from December 2019 to February 2021. Univariate and multivariate analyses were performed for stone- and patient-related factors, using the Student t and Mann-Whitney U tests for the quantitative variables and the Fisher exact and Pearson correlation tests for the qualitative variables.

Results: A total of 138 patients were eligible for this study, including 92 men and 46 women. The mean age was 38.6 ± 12.4 years, and the mean body mass index (BMI) was 25.9 ± 3.4 kg/m2. Four weeks after SWL, 120 patients (87%) were free of stones, and 18 (13%) needed further treatment. Univariate analyses showed that SFR was negatively correlated with increased BMI (p = 0.0001), maximum stone length (p = 0.0001), transverse diameter of the stone (p = 0.0001), number of shocks per session (p = 0.052), and Hounsfield unit (HU) (p = 0.0001). Multivariate analysis revealed that HU (p = 0.009), maximum stone length (p = 0.01), BMI (p = 0.000), and presence of double-J stent (p = 0.034) were independent risk factors for failure of single-session SWL in the treatment of kidney stones 10 to 20 mm in diameter. The estimated average cost per case was USD 450.5.

Conclusions: Increased HU, maximum stone length, BMI, and presence of double-J stents were independent risk factors for low SFR after single-session SWL for a kidney stone 10 to 20 mm in diameter. The cost of SWL remains an advantage in the private sector.

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来源期刊
Current Urology
Current Urology Medicine-Urology
CiteScore
2.30
自引率
0.00%
发文量
96
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