一名患有多动症和合并焦虑症的青少年因服用度洛西汀-阿托莫西汀复方制剂而引发的塔克次氏心肌病。

Q3 Medicine Psychopharmacology bulletin Pub Date : 2023-08-11

Ahmed Naguy, Bibi Alamiri

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引用次数: 0

摘要

作者报告了一例有趣的病例：一名患有注意力缺陷/多动障碍并合并广泛性焦虑症的青少年，由于选择性去甲肾上腺素再摄取抑制剂阿托西汀和抗抑郁药度洛西汀之间的药代动力学和药效学相互作用而患上了塔克次氏心肌病。临床医生在处方以去甲肾上腺素能受体为靶点的药物时，应注意其对心血管的潜在不良影响。

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Takotsubo Cardiomyopathy Related to Duloxetine-Atomoxetine Combination in an Adolescent with ADHD and Comorbid GAD.

Authors report on an interesting case of a teenager with attention-deficit/hyperactivity disorder and comorbid generalized anxiety disorder, who developed takotsubo cardiomyopathy subsequent to pharmacokinetic and pharmacodynamic interactions between atomoxetine, a selective norepinephrine reuptake inhibitor, and the antidepressant duloxetine. Clinicians should be mindful of the potential for cardiovascular adverse effects when prescribing agents that target noradrenergic receptors.

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