非洲艾滋病毒感染者2型糖尿病和肾衰竭的管理:现状和行动呼吁

IF 1.5 Q4 INFECTIOUS DISEASES HIV AIDS-Research and Palliative Care Pub Date : 2023-01-01 DOI:10.2147/HIV.S396949
Nicola Wearne, Bianca Davidson, Marc Blockman, Jackie Jones, Ian L Ross, Joel A Dave
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引用次数: 0

摘要

糖尿病(DM)和慢性肾脏疾病(CKD)的全球负担不断增加,加上艾滋病毒感染者(PWH)的高负担。由于接受抗逆转录病毒治疗的寿命延长,产妇现在面临罹患非传染性疾病(包括糖尿病)的风险。非洲是艾滋病毒感染负担最重的地区,在未来20年,糖尿病流行率将出现最大增幅。此外,越来越多的人患有慢性肾病并进展为肾衰竭。因此,迫切需要对所有3种疾病进行早期识别和管理,以防止疾病进展和并发症。这在非洲对于CKD患者尤其重要,因为那里的透析和/或移植受到限制或无法获得。本文综述了HIV感染与糖尿病相互作用的流行病学和病理生理学,以及这些疾病对CKD发生发展的影响。最后,它还旨在审查有关管理的数据,这些数据源于这三种疾病日益增加的负担。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Management of Type 2 Diabetes Mellitus and Kidney Failure in People with HIV-Infection in Africa: Current Status and a Call to Action.

There is an increasing global burden of diabetes mellitus (DM) and chronic kidney disease (CKD), coupled with a high burden of people with HIV (PWH). Due to an increased lifespan on ART, PWH are now at risk of developing non-communicable diseases, including DM. Africa has the greatest burden of HIV infection and will experience the greatest increase in prevalence of DM over the next two decades. In addition, there is a rising number of people with CKD and progression to kidney failure. Therefore, there is an urgent need for the early identification and management of all 3 diseases to prevent disease progression and complications. This is particularly important in Africa for people with CKD where there is restricted or no access to dialysis and/or transplantation. This review focuses on the epidemiology and pathophysiology of the interaction between HIV infection and DM and the impact that these diseases have on the development and progression of CKD. Finally, it also aims to review the data on the management, which stems from the growing burden of all three diseases.

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来源期刊
CiteScore
3.00
自引率
6.70%
发文量
61
审稿时长
16 weeks
期刊介绍: About Dove Medical Press Dove Medical Press Ltd is part of Taylor & Francis Group, the Academic Publishing Division of Informa PLC. We specialize in the publication of Open Access peer-reviewed journals across the broad spectrum of science, technology and especially medicine. Dove Medical Press was founded in 2003 with the objective of combining the highest editorial standards with the ''best of breed'' new publishing technologies. We have offices in Manchester and London in the United Kingdom, representatives in Princeton, New Jersey in the United States, and our editorial offices are in Auckland, New Zealand. Dr Scott Fraser is our Medical Director based in the UK. He has been in full time clinical practice for over 20 years as well as having an active research interest.
期刊最新文献
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