Richard M Thomson, Thomas H Jovic, Charlotte Eckhardt, Tomás O'Neill
{"title":"透明质酸填充剂矫正成人唇裂不对称：使用 CLEFT-Q 对技术和患者报告结果测量进行描述。","authors":"Richard M Thomson, Thomas H Jovic, Charlotte Eckhardt, Tomás O'Neill","doi":"10.1177/10556656231190532","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>To determine the efficacy of hyaluronic acid (HLA) lip filler to correct subtle cleft lip asymmetries in adults using a validated patient reported outcome measure (PROM).</p><p><strong>Design: </strong>Prospective cross sectional.</p><p><strong>Setting: </strong>UK National Health Service.</p><p><strong>Patients, participants: </strong>Over 18 years old with repaired cleft lip and dissatisfaction of their lip appearance.</p><p><strong>Interventions: </strong>HLA lip filler injection.</p><p><strong>Main outcome measures: </strong>A validated, cleft specific PROM, the lip module of CLEFT-Q™ prior to treatment and again after six weeks.</p><p><strong>Results: </strong>24 patients included. A mean total CLEFT-Q™ score pre-procedure was 14.9 (Stand deviation (SD) = 4.91) and 24 (SD = 6.08) post-procedure. Difference in mean total score pre- and post-procedure were statically significant (<i>P</i> = .0001) in all domains on the CLEFT-Q™. No adverse outcomes.</p><p><strong>Conclusion: </strong>HLA filler to correct subtle cleft lip asymmetries in adults is a simple low risk technique, which can significantly improve the patient's perception of lip appearance.</p><p><strong>Conclusion: </strong>HLA lip filler to correct subtle cleft lip asymmetries in adults is a simple technique, low risk procedure which can significantly improve the patient's perception of lip appearance.</p>","PeriodicalId":55255,"journal":{"name":"Cleft Palate-Craniofacial Journal","volume":null,"pages":null},"PeriodicalIF":1.2000,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Hyaluronic Acid Fillers to Correct Cleft Lip Asymmetry in Adults: Description of Technique and Patient Reported Outcome Measure Using CLEFT-Q.\",\"authors\":\"Richard M Thomson, Thomas H Jovic, Charlotte Eckhardt, Tomás O'Neill\",\"doi\":\"10.1177/10556656231190532\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objective: </strong>To determine the efficacy of hyaluronic acid (HLA) lip filler to correct subtle cleft lip asymmetries in adults using a validated patient reported outcome measure (PROM).</p><p><strong>Design: </strong>Prospective cross sectional.</p><p><strong>Setting: </strong>UK National Health Service.</p><p><strong>Patients, participants: </strong>Over 18 years old with repaired cleft lip and dissatisfaction of their lip appearance.</p><p><strong>Interventions: </strong>HLA lip filler injection.</p><p><strong>Main outcome measures: </strong>A validated, cleft specific PROM, the lip module of CLEFT-Q™ prior to treatment and again after six weeks.</p><p><strong>Results: </strong>24 patients included. A mean total CLEFT-Q™ score pre-procedure was 14.9 (Stand deviation (SD) = 4.91) and 24 (SD = 6.08) post-procedure. Difference in mean total score pre- and post-procedure were statically significant (<i>P</i> = .0001) in all domains on the CLEFT-Q™. No adverse outcomes.</p><p><strong>Conclusion: </strong>HLA filler to correct subtle cleft lip asymmetries in adults is a simple low risk technique, which can significantly improve the patient's perception of lip appearance.</p><p><strong>Conclusion: </strong>HLA lip filler to correct subtle cleft lip asymmetries in adults is a simple technique, low risk procedure which can significantly improve the patient's perception of lip appearance.</p>\",\"PeriodicalId\":55255,\"journal\":{\"name\":\"Cleft Palate-Craniofacial Journal\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.2000,\"publicationDate\":\"2024-11-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Cleft Palate-Craniofacial Journal\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1177/10556656231190532\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2023/7/24 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q3\",\"JCRName\":\"DENTISTRY, ORAL SURGERY & MEDICINE\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Cleft Palate-Craniofacial Journal","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1177/10556656231190532","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2023/7/24 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"DENTISTRY, ORAL SURGERY & MEDICINE","Score":null,"Total":0}
Hyaluronic Acid Fillers to Correct Cleft Lip Asymmetry in Adults: Description of Technique and Patient Reported Outcome Measure Using CLEFT-Q.
Objective: To determine the efficacy of hyaluronic acid (HLA) lip filler to correct subtle cleft lip asymmetries in adults using a validated patient reported outcome measure (PROM).
Design: Prospective cross sectional.
Setting: UK National Health Service.
Patients, participants: Over 18 years old with repaired cleft lip and dissatisfaction of their lip appearance.
Interventions: HLA lip filler injection.
Main outcome measures: A validated, cleft specific PROM, the lip module of CLEFT-Q™ prior to treatment and again after six weeks.
Results: 24 patients included. A mean total CLEFT-Q™ score pre-procedure was 14.9 (Stand deviation (SD) = 4.91) and 24 (SD = 6.08) post-procedure. Difference in mean total score pre- and post-procedure were statically significant (P = .0001) in all domains on the CLEFT-Q™. No adverse outcomes.
Conclusion: HLA filler to correct subtle cleft lip asymmetries in adults is a simple low risk technique, which can significantly improve the patient's perception of lip appearance.
Conclusion: HLA lip filler to correct subtle cleft lip asymmetries in adults is a simple technique, low risk procedure which can significantly improve the patient's perception of lip appearance.
期刊介绍：
The Cleft Palate-Craniofacial Journal (CPCJ) is the premiere peer-reviewed, interdisciplinary, international journal dedicated to current research on etiology, prevention, diagnosis, and treatment in all areas pertaining to craniofacial anomalies. CPCJ reports on basic science and clinical research aimed at better elucidating the pathogenesis, pathology, and optimal methods of treatment of cleft and craniofacial anomalies. The journal strives to foster communication and cooperation among professionals from all specialties.
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