骨骼尚未发育成熟的膝关节周围骨肉瘤切除术后肢体长度不一致的处理方法。

IF 0.9 4区 医学 Q4 ORTHOPEDICS Journal of Pediatric Orthopaedics-Part B Pub Date : 2024-09-01 Epub Date: 2023-09-11 DOI:10.1097/BPB.0000000000001124
Sean P Kelly, Dipak B Ramkumar, Brooke Crawford, Santiago A Lozano-Calderon, Mark C Gebhardt, Megan E Anderson
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引用次数: 0

摘要

骨肉瘤患者越来越多地选择肢体救治。这可能会导致骨骼不成熟的患者出现肢体长度不一致(LLD)的问题。我们将各种治疗方案归纳为一种算法,并报告了我们的结果。我们对 12 岁或以下、累及股骨干骺端至胫骨干骺端任何位置的骨肉瘤患者进行了回顾性研究。我们的临床路径规定,骺端病变的患者采用闰骨异体移植重建术,骺端病变且预期LLD小于5厘米的患者采用骨关节异体移植术,预期LLD大于5厘米的患者采用可扩展假体。20 名患者符合纳入标准:11名患者接受了骨关节异体移植,5名患者接受了可伸展假体,4名患者接受了闰层异体移植;中位年龄为11.5岁;中位随访时间为8.2年;最终中位LLD为1.6厘米。五名患者进行了对侧骨外固定术,两名患者进行了对侧股骨缩短术,可伸展假体进行了中位数为6次(4-8次)的延长术。四名患者的残余 LLD 超过 3 厘米。8名患者进行了13次翻修,2人截肢。小儿膝关节骨肉瘤的肢体修复可采用多种技术,在LLD方面取得令人满意的效果。鉴于肢体缺损和重建失败的二次手术率很高,因此必须进行仔细的术前规划和共同决策。证据等级:三级回顾性比较研究。
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Management of limb length discrepancy after bone sarcoma resection about the knee in the skeletally immature.

Patients with bone sarcomas increasingly choose limb salvage. This can lead to issues with limb length discrepancy (LLD) for the skeletally immature. We synthesize management options into an algorithm and report our results. Patients with bone sarcomas involving any location from the femoral diaphysis to the tibial diaphysis 12 years or younger were reviewed. Our clinical pathway prescribed patients with metadiaphyseal lesions to intercalary allograft reconstruction, epiphyseal lesions and less than 5 cm expected LLD to osteoarticular allograft and patients with more than 5 cm expected LLD to extendable prosthesis. Twenty patients met inclusion criteria: 11 with osteoarticular allografts, 5 with extendable prostheses and 4 with intercalary allografts; median age 11.5 years; median follow-up 8.2 years; and final median LLD 1.6 cm. Five patients had contralateral epiphysiodesis, two patients underwent contralateral femoral shortening and a median of 6 (range 4-8) lengthenings were performed for extendable prostheses. Four patients had residual LLD over 3 cm. There were 13 revisions in 8 patients and 2 amputations. Limb-salvage in paediatric bone sarcoma of the knee can be managed with multiple techniques producing satisfactory results in regards to LLD. Careful pre-operative planning and shared decision making is a requisite given the high rate of secondary procedures for both LLD and reconstructive failures. Level of evidence: Level III Retrospective Comparative Study.

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来源期刊
CiteScore
2.20
自引率
9.10%
发文量
170
审稿时长
4-8 weeks
期刊介绍: The journal highlights important recent developments from the world''s leading clinical and research institutions. The journal publishes peer-reviewed papers on the diagnosis and treatment of pediatric orthopedic disorders. It is the official journal of IFPOS (International Federation of Paediatric Orthopaedic Societies). Submitted articles undergo a preliminary review by the editor. Some articles may be returned to authors without further consideration. Those being considered for publication will undergo further assessment and peer-review by the editors and those invited to do so from a reviewer pool. ​
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