生物合成纳米颗粒:癌症治疗的新方法。

Vivek K Chaturvedi, Bhaskar Sharma, Abhay Dev Tripathi, Dawesh P Yadav, Kshitij Rb Singh, Jay Singh, Ravindra Pratap Singh
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引用次数: 0

摘要

纳米技术已经成为现代科学和癌症治疗中最快速、创新和适应性最强的科学之一。传统化疗由于其非特异性和对健康细胞的不良副作用而具有局限性,并且仍然是一个严重的全球健康问题。由于纳米颗粒具有特异性靶向癌细胞并直接向其输送治疗化学物质的能力,因此它们已成为癌症治疗的一种可行策略。纳米材料揭示了基于尺寸、分布和形状的新特性。生物合成或生物源纳米颗粒是一种具有抗癌能力的新技术,如触发癌细胞凋亡和减缓肿瘤生长。它们可以被配置为向特定的癌细胞或肿瘤标志物输送药物或其他疗法。尽管具有潜力,生物合成纳米粒子仍面临着发展障碍,如合成和表征方面缺乏标准化,可能存在毒性,以及它们对各种癌症的有效性。生物合成纳米颗粒的有效性和安全性,以及它们最成功对抗的癌症类型,都必须进一步研究。这篇综述讨论了生物合成纳米颗粒作为一种新的癌症治疗方法的前景,以及它们的作用模式和目前发展的障碍。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Biosynthesized nanoparticles: a novel approach for cancer therapeutics.

Nanotechnology has become one of the most rapid, innovative, and adaptable sciences in modern science and cancer therapy. Traditional chemotherapy has limits owing to its non-specific nature and adverse side effects on healthy cells, and it remains a serious worldwide health issue. Because of their capacity to specifically target cancer cells and deliver therapeutic chemicals directly to them, nanoparticles have emerged as a viable strategy for cancer therapies. Nanomaterials disclose novel properties based on size, distribution, and shape. Biosynthesized or biogenic nanoparticles are a novel technique with anti-cancer capabilities, such as triggering apoptosis in cancer cells and slowing tumour growth. They may be configured to deliver medications or other therapies to specific cancer cells or tumour markers. Despite their potential, biosynthesized nanoparticles confront development obstacles such as a lack of standardisation in their synthesis and characterization, the possibility of toxicity, and their efficiency against various forms of cancer. The effectiveness and safety of biosynthesized nanoparticles must be further investigated, as well as the types of cancer they are most successful against. This review discusses the promise of biosynthesized nanoparticles as a novel approach for cancer therapeutics, as well as their mode of action and present barriers to their development.

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