1999-2015 年米非司酮化学流产和手术流产后急诊室使用情况纵向队列研究。

IF 1.5 Q3 HEALTH POLICY & SERVICES Health Services Research and Managerial Epidemiology Pub Date : 2021-11-09 eCollection Date: 2021-01-01 DOI:10.1177/23333928211053965
James Studnicki, Donna J Harrison, Tessa Longbons, Ingrid Skop, David C Reardon, John W Fisher, Maka Tsulukidze, Christopher Craver
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引用次数: 0

摘要

导言:关于人工流产后急诊就诊情况的现有研究很少,而且受方法的限制,低估了人工流产后不良事件的发生率。自 2000 年食品及药物管理局批准化学流产以来,流产后急诊室(ER)的使用情况可以确定化学流产与手术流产的相对发病率趋势:完成第一项关于化学和手术流产后急诊室使用情况的纵向队列研究:1999-2015年间,在17个为人工流产提供公共资助的州中,有423 000例经证实的人工流产和121 283例随后在手术后30天内的急诊就诊:在化学流产而非手术流产后,急诊就诊的风险更高:所有急诊就诊(OR 1.22,CL 1.19-1.24);误码自然流产(OR 1.88,CL 1.81-1.96);流产相关(OR 1.53,CL 1.49-1.58)。每 1000 例人工流产中,化学流产的急诊就诊率增长较快,到 2015 年,所有急诊就诊中,化学流产与手术流产的就诊率分别为 354.8 与 357.9;误编码自然流产的就诊率分别为 31.5 与 8.6;人工流产相关就诊率分别为 51.7 与 22.0。人工流产相关就诊人次占总就诊人次的比例是化学流产的两倍,到 2015 年达到 14.6%。误编码的自然流产就诊人次占总就诊人次的比例是化学流产的近 4 倍,到 2015 年,误编码的自然流产就诊人次占总就诊人次的 8.9%,占人工流产相关就诊人次的 60.9%:结论:任何人工流产后急诊就诊的发生率和每次人工流产的就诊率都在增长,但与手术流产相比,化学人工流产与人工流产后急诊就诊的发病率持续且逐渐增加。还有一个明显的趋势是,越来越多的妇女在化学流产后被误诊为在急诊室接受自然流产治疗。
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A Longitudinal Cohort Study of Emergency Room Utilization Following Mifepristone Chemical and Surgical Abortions, 1999-2015.

Introduction: Existing research on postabortion emergency room visits is sparse and limited by methods which underestimate the incidence of adverse events following abortion. Postabortion emergency room (ER) use since Food and Drug Administration approval of chemical abortion in 2000 can identify trends in the relative morbidity burden of chemical versus surgical procedures.

Objective: To complete the first longitudinal cohort study of postabortion emergency room use following chemical and surgical abortions.

Methods: A population-based longitudinal cohort study of 423 000 confirmed induced abortions and 121,283 subsequent ER visits occurring within 30 days of the procedure, in the years 1999-2015, to Medicaid-eligible women over 13 years of age with at least one pregnancy outcome, in the 17 states which provided public funding for abortion.

Results: ER visits are at greater risk to occur following a chemical rather than a surgical abortion: all ER visits (OR 1.22, CL 1.19-1.24); miscoded spontaneous (OR 1.88, CL 1.81-1.96); and abortion-related (OR 1.53, CL 1.49-1.58). ER visit rates per 1000 abortions grew faster for chemical abortions, and by 2015, chemical versus surgical rates were 354.8 versus 357.9 for all ER visits; 31.5 versus 8.6 for miscoded spontaneous abortion visits; and 51.7 versus 22.0 for abortion-related visits. Abortion-related visits as a percent of total visits are twice as high for chemical abortions, reaching 14.6% by 2015. Miscoded spontaneous abortion visits as a percent of total visits are nearly 4 times as high for chemical abortions, reaching 8.9% of total visits and 60.9% of abortion-related visits by 2015.

Conclusion: The incidence and per-abortion rate of ER visits following any induced abortion are growing, but chemical abortion is consistently and progressively associated with more postabortion ER visit morbidity than surgical abortion. There is also a distinct trend of a growing number of women miscoded as receiving treatment for spontaneous abortion in the ER following a chemical abortion.

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CiteScore
1.60
自引率
6.20%
发文量
32
审稿时长
12 weeks
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