最大限度地提高单层纸的流速，快速流动的微流体纸基分析设备。

IF 2.3 4区工程技术 Q2 INSTRUMENTS & INSTRUMENTATION Microfluidics and Nanofluidics Pub Date : 2023-09-13 DOI:10.1007/s10404-023-02679-8

Iain Macleod Briongos, Zachary D. Call, Charles S. Henry, David L. Bark Jr.

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引用次数: 0

摘要

小型单层微流体纸基分析设备（µPAD）为一系列护理点应用提供了潜力；然而，它们被限制在低流速。在这里，我们研究了激光切割纸通道在流体体积有限的小型设备中最大化流速的作用。我们证明，与单次切割相比，分支激光切割凹槽的流速可提高59.23-73.98%，与单独的纸张相比，流速可提高435%。这些设计考虑因素可以应用于更复杂的微流体设备，目的是提高流速，并可用于独立的自泵通道。补充信息：在线版本包含补充材料，可在10.1007/s10404-023-02679-8上获得。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Maximizing flow rate in single paper layer, rapid flow microfluidic paper-based analytical devices

Small, single-layer microfluidic paper-based analytical devices (µPADs) offer potential for a range of point-of-care applications; however, they have been limited to low flow rates. Here, we investigate the role of laser cutting paper channels in maximizing flow rate in small profile devices with limited fluid volumes. We demonstrate that branching, laser-cut grooves can provide a 59.23–73.98% improvement in flow rate over a single cut, and a 435% increase over paper alone. These design considerations can be applied to more complex microfluidic devices with the aim of increasing the flow rate, and could be used in stand-alone channels for self-pumping.

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来源期刊

Microfluidics and Nanofluidics 工程技术-纳米科技

CiteScore

4.80

自引率

3.60%

发文量

审稿时长

2 months

期刊介绍： Microfluidics and Nanofluidics is an international peer-reviewed journal that aims to publish papers in all aspects of microfluidics, nanofluidics and lab-on-a-chip science and technology. The objectives of the journal are to (1) provide an overview of the current state of the research and development in microfluidics, nanofluidics and lab-on-a-chip devices, (2) improve the fundamental understanding of microfluidic and nanofluidic phenomena, and (3) discuss applications of microfluidics, nanofluidics and lab-on-a-chip devices. Topics covered in this journal include: 1.000 Fundamental principles of micro- and nanoscale phenomena like, flow, mass transport and reactions 3.000 Theoretical models and numerical simulation with experimental and/or analytical proof 4.000 Novel measurement & characterization technologies 5.000 Devices (actuators and sensors) 6.000 New unit-operations for dedicated microfluidic platforms 7.000 Lab-on-a-Chip applications 8.000 Microfabrication technologies and materials Please note, Microfluidics and Nanofluidics does not publish manuscripts studying pure microscale heat transfer since there are many journals that cover this field of research (Journal of Heat Transfer, Journal of Heat and Mass Transfer, Journal of Heat and Fluid Flow, etc.).