用狗尸体的体重或脊柱长度计算染料和造影剂的硬膜外体积。

IF 1.1 4区 农林科学 Q2 Veterinary Canadian journal of veterinary research = Revue canadienne de recherche veterinaire Pub Date : 2023-07-01
Flavio A V Freitag, Alexander Valverde, Monica Jensen, Andrea Sanchez, Diego E Gomez, Craig Bailey
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引用次数: 0

摘要

本研究的目的是比较22具狗尸体中染料和造影剂混合物的腰骶硬膜外体积的鼻侧扩散,使用体重(BW)或脊柱长度(LE)计算。这些狗的体重为4.6至52.0公斤。狗的体重和体重差小于10%,体况评分(BCS)相同。对犬在胸骨平躺时通过硬膜外导管注射碘帕美醇和染料的体积混合物,根据BW计算:其中一具尸体0.2 mL/kg,根据LE计算:0.05 mL/cm (< 50 cm), 0.07 mL/cm(50至< 70 cm), 0.08 mL/cm(70至< 80 cm)和0.11 mL/cm(≥80 cm)。采用计算机断层扫描法检查碘帕美,解剖解剖法检查染色。采用混合线性模型比较每只狗体内染料和iopamidol的含量,以及配对对内体重和体重的差异(P < 0.05)。在BW和LE中,染料到达的椎骨数均大于iopamidol到达的椎骨数,但在所有对BW和LE之间,吻侧扩散无显著差异。总之,染料往往比iopamidol扩散得更远,因此,这两种方法在研究中使用时不应被认为是可互换的。
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Rostral spread of lumbosacral epidural volumes of dye and contrast medium calculated using body weight or length of the vertebral column in dog cadavers.

The objective of this study was to compare the rostral spread of lumbosacral epidural volumes of a mixture of dye and contrast medium, calculated using body weight (BW) or vertebral column length (LE), in 22 dog cadavers. The dogs weighed 4.6 to 52.0 kg. Dogs were paired within a < 10% difference for BW and LE and with the same body condition score (BCS). Pairs of dogs were injected while in sternal recumbency through an epidural catheter with a volume mixture of iopamidol and dye, calculated based on BW: 0.2 mL/kg in one of the cadavers and based on LE: 0.05 mL/cm (< 50 cm), 0.07 mL/cm (50 to < 70 cm), 0.08 mL/cm (70 to < 80 cm), and 0.11 mL/cm (≥ 80 cm) in the other cadaver. The extent of rostral spread was determined using computed tomography for iopamidol and anatomical dissection for dye. Comparisons for dye and iopamidol within each dog, and for BW and LE within matched pairs, were completed with mixed linear models (P < 0.05). The number of vertebrae reached by dye was greater than the number reached by iopamidol in both BW and LE, but the rostral spread was not significantly different between BW and LE for all pairs. In conclusion, dye tends to spread further than iopamidol and therefore, these two methods should not be considered interchangeable when used in research studies.

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来源期刊
CiteScore
1.80
自引率
0.00%
发文量
58
审稿时长
>24 weeks
期刊介绍: The Canadian Journal of Veterinary Research, published by the Canadian Veterinary Medical Association, is Canada''s only veterinary research publication. This quarterly peer-reviewed online-only journal has earned a wide international readership through the publishing of high quality scientific papers in the field of veterinary medicine. The Journal publishes the results of original research in veterinary and comparative medicine.
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