Desmodium物种分离出的黄酮类化合物的治疗作用

IF 2.2 4区 医学 Q3 MEDICINE, RESEARCH & EXPERIMENTAL Current molecular medicine Pub Date : 2024-01-01 DOI:10.2174/1566524023666221213111851
Vedpal Singh, Rohit Singh, Manish Pal Singh, Archita Katrolia
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引用次数: 0

摘要

次生代谢物是在社会中发挥重要作用的重要组成部分,它是从植物黄酮类化合物中分离出来的,对治疗人类的各种疾病非常有用。它们被广泛用作食品和营养补充剂以及抗氧化剂。传统上,Desmodium 种类是次生代谢物治疗各种疾病的重要工具。Desmodium triquetrum(豆科)是印度药用植物之一,被广泛用于治疗哮喘和炎症。从 Desmodium triquetrum Linn 中分离出的三种类黄酮,即黄芩苷、柚皮苷和新橙皮苷,可作为抗氧化剂、食品和营养补充剂,帮助人体有效运作,同时保护人体免受毒素和压力的侵害。类黄酮的作用可能是由于其中含有酚类化合物。同样,从Desmodium gangeticum物种中分离出来的类黄酮,如gangetin、gangetinin、desmocarpin和desmodin,具有抗利什曼病、抗氧化、抗关节炎和免疫调节活性。此外,从 Desmodium triflorum 中分离出的黄酮类化合物具有抗菌、抗癫痫、抗真菌和放射保护活性。因此,本研究的目的是根据文献中对Desmodium物种的描述,认识到黄酮类化合物作为膳食食品补充剂和治疗用途对人类健康的重要性。
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Therapeutic Role of Desmodium Species on its Isolated Flavonoids.

Secondary metabolites are an important part to play a major role in society and it was isolated from plant flavonoids and useful in the treatment of various kinds of diseases in the human race. They are widely used as food and nutrition supplements as well as antioxidants. Traditionally, the Desmodium species are an important tool for the secondary metabolites to treat various diseases. Desmodium triquetrum (Fabaceae) one of the Indian medicinal plants is widely used in the treatment of asthma and inflammation. Three flavonoids isolated from Desmodium triquetrum Linn namely Baicalein, Naringin and Neohesperidin are useful as antioxidants, food and nutrition supplements, that help the body to function efficiently while protecting it against toxins as well stressors. The role of flavonoids may be due to the presence of the phenolic compound. Similarly, the flavonoids such as gangetin, gangetinin, desmocarpin and desmodin isolated from the species Desmodium gangeticum are responsible for antileishmanial, antioxidant, anti-arthritic, and immunomodulatory activities. Additionally, isolated flavanoids from the species Desmodium triflorum show antibacterial, antiepileptic, antifungal, and radioprotective activities. So, the aim of the present study, based on the literature miming from the desmodium species is to acknowledge the importance of flavonoids in human health as dietary food supplements and therapeutic uses.

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来源期刊
Current molecular medicine
Current molecular medicine 医学-医学:研究与实验
CiteScore
5.00
自引率
4.00%
发文量
141
审稿时长
4-8 weeks
期刊介绍: Current Molecular Medicine is an interdisciplinary journal focused on providing the readership with current and comprehensive reviews/ mini-reviews, original research articles, short communications/letters and drug clinical trial studies on fundamental molecular mechanisms of disease pathogenesis, the development of molecular-diagnosis and/or novel approaches to rational treatment. The reviews should be of significant interest to basic researchers and clinical investigators in molecular medicine. Periodically the journal invites guest editors to devote an issue on a basic research area that shows promise to advance our understanding of the molecular mechanism(s) of a disease or has potential for clinical applications.
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