针刺治疗犬犬瘟热病毒神经后遗症的疗效观察。

IF 0.9 Q4 INTEGRATIVE & COMPLEMENTARY MEDICINE Journal of Acupuncture and Meridian Studies Pub Date : 2022-08-31 DOI:10.51507/j.jams.2022.15.4.238
Bianca P C R Santos, Jean G F Joaquim, Renata Navarro Cassu, José C F Pantoja, Stelio Pacca Loureiro Luna
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引用次数: 0

摘要

背景:针灸(AP)已被临床应用于缓解犬瘟热病毒(CDV)感染后的神经症状。目的:本临床研究旨在探讨AP联合电针(EA)对CDV感染犬神经功能的影响。方法:选取24只伴有神经系统后遗症的cdv感染犬,每周进行AP/EA切片,为期24周。在每次AP/EA会议前使用改进的评分系统评估神经系统的改善。采用McNemar检验、Friedman检验、Fisher精确检验和Kaplan-Meier曲线对数据进行分析(p < 0.05)。结果:与治疗前评分相比,AP/EA治疗后7 ~ 24周神经学评分有所改善(p < 0.001)。随着时间的推移,肢体功能恢复、颅神经缺损、精神状态(p = 0.025 - 0.014)和泌尿功能(p < 0.001)均有显著改善。分别有75%和25%的狗的肌阵挛得到改善和完全逆转。治疗结束时,本体感觉、姿势、跳跃反应正常(p < 0.001)和浅表疼痛感觉反应正常(p = 0.004)的比例均高于治疗前。结论:AP/EA治疗可显著促进cdv感染犬的神经功能恢复,可考虑在疾病的慢性期改善运动和感觉康复。然而,这些结果是初步的,必须通过进一步的调查来证实。
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Effects of Acupuncture in the Treatment of Dogs with Neurological Sequels of Distemper Virus.

Background: Acupuncture (AP) has been empirically used to relieve post-canine distemper virus (CDV) infection neurological signs in veterinary clinics.

Objectives: This clinical study aimed to investigate the effects of AP combined with electroacupuncture (EA) on neurological function in dogs infected by CDV.

Methods: Twenty-four CDV-infected dogs with neurological sequelae were recruited to receive weekly AP/EA sections for 24 weeks. Neurological improvements were assessed before each AP/EA session using a modified scoring system. Data were analyzed using the McNemar test, Friedman test, Fisher's exact test, and Kaplan-Meier curves (p < 0.05).

Results: Neurological scores improved from seven to 24 weeks after AP/EA treatment compared with pretreatment scores (p < 0.001). Significant improvements were recorded over time for functional limb recovery, cranial nerve deficits, mental status (p = 0.025 - 0.014), and urinary function (p < 0.001). Myoclonus was improved and entirely reversed in 75% and 25% of the dogs, respectively. At the end of treatment, the proportion of dogs with normal proprioception, posture, hopping (p < 0.001), and superficial pain sensation responses (p = 0.004) was greater than pretreatment values.

Conclusion: AP/EA therapy promoted significant neurological recovery in CDV-infected dogs and may be considered within the chronic phase of the disease to improve motor and sensory rehabilitation. However, these results are preliminary and must be confirmed by further investigations.

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来源期刊
Journal of Acupuncture and Meridian Studies
Journal of Acupuncture and Meridian Studies INTEGRATIVE & COMPLEMENTARY MEDICINE-
CiteScore
1.50
自引率
10.00%
发文量
35
审稿时长
12 weeks
期刊介绍: The Journal of Acupuncture and Meridian Studies is a quarterly, peer-reviewed journal featuring high-quality studies related to basic and clinical acupuncture and meridian research. It also includes new paradigm of integrative research, covering East–West and traditional–modern medicine. Manuscripts should fall into one of the categories: topical review, original research paper, brief ... click here for full Aims & Scope The Journal of Acupuncture and Meridian Studies is a quarterly, peer-reviewed journal featuring high-quality studies related to basic and clinical acupuncture and meridian research. It also includes new paradigm of integrative research, covering East–West and traditional–modern medicine.
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