主动脉夹层的性别差异:风险和结果的前瞻性分析。

Pub Date : 2023-07-01 DOI:10.2478/jccm-2023-0024
Cosmin Banceu, Marius Harpa, Klara Brinzaniuc, Ioan Tilea, Andreea Varga, Mirela Liana Gliga, Septimiu Voidazan, Nicolae Neagu, Dan Alexandru Szabo, Diana Banceu, Daiana Cristutiu, Ionut Alexandru Balmos, Alexandra Puscas, Marvin Oprean, Horatiu Suciu
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引用次数: 0

摘要

主动脉夹层(AD)是一种严重的心血管疾病,可能会产生负面影响。我们的研究采用前瞻性设计,检查了术前、围手术期和术后的数据,以评估性别对各种医疗状况的影响。我们研究了性别如何影响主动脉夹层(AD)的结果。与女性患者相比,男性患者有更多的全身性高血压(p=0.031),心包积血(p=0.003)、肺动脉高压(p=0.039)和心包积血(p=0.003)发生率更高。术中给药多巴酚丁胺显著提高了死亡风险(p=0.015)。在71 ~ 80岁年龄组中,女性患者明显多于男性(p=0.01)。年龄(p=0.004)、入院时eGFR (p=0.009)和出院时eGFR (p=0.006)均有显著差异,但性别与死亡率无相关性。总之,我们的研究结果强调,性别可能不再像我们以前认为的那样是主动脉夹层疾病的一个重要方面,这一信息可能对外科医生和参与急性主动脉夹层治疗的麻醉师有重要贡献。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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The Gender Gap in Aortic Dissection: A Prospective Analysis of Risk and Outcomes.

Aortic dissection (AD) is a severe cardiovascular condition that could have negative consequences. Our study employed a prospective design and examined preoperative, perioperative, and postoperative data to evaluate the effects of gender on various medical conditions. We looked at how gender affected the results of aortic dissection (AD). In contrast to female patients who had more systemic hypertension (p=0.031), male patients had higher rates of hemopericardium (p=0.003), pulmonary hypertension (p=0.039), and hemopericardium (p=0.003). Dobutamine administration during surgery significantly raised the mortality risk (p=0.015). There were noticeably more women patients (p=0.01) in the 71 to 80 age group. Significant differences in age (p=0.004), eGFR at admission (p=0.009), and eGFR at discharge (p=0.006) were seen, however, there was no association between gender and mortality. In conclusion, our findings highlight that gender may no longer be such an important aspect of aortic dissection disease as we previously thought, and this information could have an important contribution for surgeons as well as for anesthesiologists involved in the management of acute aortic dissection.

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