大型社区儿童和青少年样本中的睡眠问题和自闭症障碍。

IF 4.6 Q2 MATERIALS SCIENCE, BIOMATERIALS ACS Applied Bio Materials Pub Date : 2024-10-01 Epub Date: 2022-12-14 DOI:10.1007/s10578-022-01470-0
Jared M Saletin, M Elisabeth Koopman-Verhoeff, Gloria Han, David H Barker, Mary A Carskadon, Thomas F Anders, Stephen J Sheinkopf
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引用次数: 0

摘要

睡眠问题在自闭症谱系障碍(ASD)患者中很常见。睡眠问题如何反映特定的 ASD 表型尚不清楚。我们研究了睡眠问题是否能反映自闭症谱系障碍患者的功能障碍。我们分析了来自罗德岛自闭症研究和治疗联盟数据集的 977 名原发性患者(女性 233 人;年龄 = 11.27 ± 4.13 岁)。我们发现,确诊为自闭症的患者更容易出现睡眠问题。然而,在整个样本中,除了正式诊断之外,睡眠问题还与更严重的社交障碍和更差的适应功能相关。通过使用一个反映社区中各种表现的大型数据集,本研究强调了在临床实践中考虑睡眠问题以改善 ASD 患者适应功能的重要性。
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Sleep Problems and Autism Impairments in a Large Community Sample of Children and Adolescents.

Sleep problems are common in individuals with autism spectrum disorder (ASD). How sleep problems reflect specific ASD phenotypes is unclear. We studied whether sleep problems indexed functional impairment in a heterogeneous community sample of individuals with ASD. We analyzed 977 probands (233 females; age = 11.27 ± 4.13 years) from the Rhode Island Consortium for Autism Research and Treatment dataset, a unique public-private-academic collaboration involving all major points of service for families in Rhode Island. We found that individuals with a confirmed diagnosis of ASD were more likely to have sleep problems. However, across the whole sample and above and beyond a formal diagnosis, sleep problems were dimensionally associated with worse social impairment and poorer adaptive functioning. By using a large dataset reflective of the diversity of presentations in the community, this study underscores the importance of considering sleep problems in clinical practice to improve adaptive functioning in individuals with ASD.

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来源期刊
ACS Applied Bio Materials
ACS Applied Bio Materials Chemistry-Chemistry (all)
CiteScore
9.40
自引率
2.10%
发文量
464
期刊最新文献
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