柑橘Tristeza病毒:从病原体到灵丹妙药。

IF 8.1 1区 医学 Q1 VIROLOGY Annual Review of Virology Pub Date : 2022-09-29 DOI:10.1146/annurev-virology-100520-114412
Svetlana Y Folimonova, Yong-Duo Sun
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引用次数: 4

摘要

柑橘tristeza virus (CTV)是柑橘最具破坏性的病毒病原体。在过去的一个世纪里,CTV在世界各地的柑橘种植区引起了严重的流行病,造成了1亿多棵树的损失。目前,该病毒继续威胁着许多不同国家的柑橘生产。由于CTV的RNA基因组较大,寄主范围狭窄,仅局限于生长缓慢的柑橘类及其近缘种,以及CTV种群的复杂性,CTV的研究面临着独特的挑战。尽管存在这些障碍,但在了解ctv -宿主相互作用以及将病毒转化为作物保护和改良工具方面取得了显著进展。本文综述了近年来有关CTV感染机制的研究进展。了解这些机制对于开发控制CTV疾病的手段并最终将该病毒转化为盟友至关重要。
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Citrus Tristeza Virus: From Pathogen to Panacea.

Citrus tristeza virus (CTV) is the most destructive viral pathogen of citrus. During the past century, CTV induced grave epidemics in citrus-growing areas worldwide that have resulted in a loss of more than 100 million trees. At present, the virus continues to threaten citrus production in many different countries. Research on CTV is accompanied by distinctive challenges stemming from the large size of its RNA genome, the narrow host range limited to slow-growing Citrus species and relatives, and the complexity of CTV populations. Despite these hurdles, remarkable progress has been made in understanding the CTV-host interactions and in converting the virus into a tool for crop protection and improvement. This review focuses on recent advances that have shed light on the mechanisms underlying CTV infection. Understanding these mechanisms is pivotal for the development of means to control CTV diseases and, ultimately, turn this virus into an ally.

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来源期刊
CiteScore
19.40
自引率
0.90%
发文量
28
期刊介绍: The Annual Review of Virology serves as a conduit for disseminating thrilling advancements in our comprehension of viruses spanning animals, plants, bacteria, archaea, fungi, and protozoa. Its reviews illuminate novel concepts and trajectories in basic virology, elucidating viral disease mechanisms, exploring virus-host interactions, and scrutinizing cellular and immune responses to virus infection. These reviews underscore the exceptional capacity of viruses as potent probes for investigating cellular function.
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