散发性小前庭神经鞘瘤的早期手术及最终治愈。

IF 2.1 4区 医学 Q2 OTORHINOLARYNGOLOGY Acta Otorhinolaryngologica Italica Pub Date : 2022-10-01 DOI:10.14639/0392-100X-N2322
Elisabetta Zanoletti, Stefano Concheri, Giulia Tealdo, Diego Cazzador, Luca Denaro, Domenico d'Avella, Antonio Mazzoni
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引用次数: 2

摘要

目的:报道一例散发性小前庭神经鞘瘤的手术治疗结果,并探讨早期手术治疗的作用。方法:对234例经迷路或保听手术治疗的前庭神经鞘瘤患者进行回顾性分析。观察指标为疾病控制、术后面神经功能、并发症及听力。结果:经迷路入路占59%,保听手术占40%,经气管入路占1%。100%的病例完全切除。总体而言,术后主要和次要并发症发生率为8.5%,完全恢复,无后遗症。95%的患者术后1年面神经功能达到House-Brackmann评分(HB) 1-2。东京分类中A-B-C级听力保留率为70%,AAOHNS分类中AB级听力保留率为77%。结论:早期手术治疗小前庭神经鞘瘤是一种有效的选择,其功能预后良好,发病率低,治愈率高。与文献报道的非手术治疗相比,早期手术与更好的预后相关。
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Early surgery and definitive cure in small sporadic vestibular schwannoma.

Objective: To report surgical outcomes of a cohort of small sporadic vestibular schwannoma and discuss the role of early surgery.

Methods: Retrospective descriptive analysis of 234 consecutive patients with small vestibular schwannoma operated on with translabyrinthine or hearing preservation surgical approaches. Outcome measures were control of disease, postoperative facial nerve function, complications and hearing outcome.

Results: A translabyrinthine approach was performed in 59% of cases, hearing preservation surgery in 40% and transmeatal approach in 1%, respectively. Complete resection was achieved in 100% of cases. Overall, postoperative major and minor complications were 8.5% in the series, with complete recovery and no sequalae. Facial nerve function at one year postoperatively was House-Brackmann scale (HB) 1-2 in 95% of cases. The rate of hearing preservation was 70% A-B-C classes of Tokyo classification and 77% AB classes of AAOHNS classification.

Conclusions: Early surgery in small vestibular schwannoma is a valid option, due to good functional outcomes, low morbidity and definitive cure. Early surgery is associated with better outcomes when considered in relation to non-surgical treatments reported in the literature.

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来源期刊
Acta Otorhinolaryngologica Italica
Acta Otorhinolaryngologica Italica OTORHINOLARYNGOLOGY-
CiteScore
3.40
自引率
10.00%
发文量
97
审稿时长
6-12 weeks
期刊介绍: Acta Otorhinolaryngologica Italica first appeared as “Annali di Laringologia Otologia e Faringologia” and was founded in 1901 by Giulio Masini. It is the official publication of the Italian Hospital Otology Association (A.O.O.I.) and, since 1976, also of the Società Italiana di Otorinolaringoiatria e Chirurgia Cervico-Facciale (S.I.O.Ch.C.-F.). The journal publishes original articles (clinical trials, cohort studies, case-control studies, cross-sectional surveys, and diagnostic test assessments) of interest in the field of otorhinolaryngology as well as clinical techniques and technology (a short report of unique or original methods for surgical techniques, medical management or new devices or technology), editorials (including editorial guests – special contribution) and letters to the Editor-in-Chief. Articles concerning science investigations and well prepared systematic reviews (including meta-analyses) on themes related to basic science, clinical otorhinolaryngology and head and neck surgery have high priority.
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