编辑导言:与精神疾病相关的动物模型。

IF 3.4 Q2 BIOCHEMISTRY & MOLECULAR BIOLOGY Emerging Topics in Life Sciences Pub Date : 2022-12-09 DOI:10.1042/ETLS20220094
Amy L Milton
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引用次数: 0

摘要

精神疾病影响着全球相当一部分人口,而目前可用的治疗方法并非对所有患者都有效。了解精神疾病的心理和生物机制将有助于治疗方法的开发,而转化动物模型的使用则有可能为此带来变革。本特刊围绕美国国立精神卫生研究所的 "研究领域标准"(RDoC)方法,展示了如何最好地利用动物模型来了解和治疗精神疾病的过程的综述。
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Editorial introduction: animal models relevant to mental health disorders.

Mental health disorders affect a substantial proportion of the worldwide population, and currently available treatments do not work for all affected individuals. Understanding the psychological and biological mechanisms that underlie mental health disorders will facilitate treatment development, and the use of translational animal models is potentially transformative for this. Structured around the US National Institute of Mental Health's 'Research Domain Criteria' (RDoC) approach, this special issue showcases reviews that consider how animal models can best be used to understand and treat the processes that go awry in mental health disorders.

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