在安全网络机构中提高质量的努力:增加糖尿病筛查与诊断时较低的HbA1c和改善2型糖尿病青年患者的HbA1c结果相关。

IF 3.9 3区 医学 Q2 ENDOCRINOLOGY & METABOLISM Pediatric Diabetes Pub Date : 2022-12-01 DOI:10.1111/pedi.13438
Kathy Love-Osborne, Haley Ringwood, Jeanelle Sheeder, Phil Zeitler
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引用次数: 1

摘要

目的:评估青少年糖尿病筛查增加是否与T2D诊断时HbA1c降低和改善青少年HbA1c结局相关。研究设计与方法:计算2009 - 2018年糖尿病筛查率。电子医疗记录确定了2009年至2018年8-18岁首次HbA1c≥6.5%的肥胖青年;海图检查确认事故T2D。收集患者的人口统计学、BMI和HbA1c值,以及血糖仪和糖尿病药物的使用情况。结果:青年人T2D 142例。中位年龄为14岁(范围8-18岁);58%是女性。46%在第一次HbA1c检测中被发现。69例(49%)有1日糖化血红蛋白6.5% - -6.9%,43(30%)7.0% -7.9%,30(21%)≥8%。从第一次到最后一次HbA1c的随访中位数为2.6年(范围0-10)。121名青年在诊断后随访≥1年;其中,87人(72%)的HbA1c持续处于t2d范围或正在服用糖尿病药物。HbA1c≥7%的青年患者中有85%有持续性T2D,而HbA1c≥7%的青年患者中有52%有持续性T2D
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Quality improvement efforts in a safety net institution: Increased diabetes screening is associated with lower HbA1c at diagnosis and improved HbA1c outcomes in youth with type 2 diabetes.

Objectives: Evaluate whether increased diabetes screening in youth is associated with lower HbA1c at T2D diagnosis and improved HbA1c outcomes in youth.

Research design and methods: Diabetes screening rates from 2009 to 2018 were calculated. Electronic medical records identified obese youth ages 8-18 with first HbA1c ≥6.5% from 2009 to 2018; chart review confirmed incident T2D. Demographics, BMI and HbA1c values, and use of glucometer and diabetes medications were collected.

Results: 142 youth had T2D. Median age was 14 years (range 8-18); 58% were female. 46% were identified on first HbA1c testing. 69 (49%) had 1st HbA1c 6.5%-6.9%, 43 (30%) 7.0%-7.9%, and 30 (21%) ≥8%. Follow-up from 1st to last HbA1c was median 2.6 years (range 0-10). 121 youth had follow-up testing ≥1 year after diagnosis; of these, 87 (72%) had persistent T2D-range HbA1c or were taking diabetes medications. 85% of youth with 1st HbA1c ≥7% had persistent T2D versus 52% of those with 1st HbA1c <7% (p < 0.001). Poorly controlled diabetes at last test was present in 19% of youth with baseline HbA1c 6.5%-6.9%, 30% with 7.0%-7.9%, and 63% with ≥8% (p < 0.001). 47 (68%) with HbA1c <7% were prescribed a glucometer; 9% of youth prescribed a meter and 41% of youth not prescribed a meter had poorly controlled diabetes at last test (p = 0.009).

Conclusions: Youth with HbA1c <7% at diagnosis were less likely to have poorly controlled diabetes at follow-up. Prescription of glucometers for youth with HbA1c in this range was associated with improved HbA1c outcomes and deserves further study including components of glucometer teaching.

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来源期刊
Pediatric Diabetes
Pediatric Diabetes 医学-内分泌学与代谢
CiteScore
6.60
自引率
14.70%
发文量
141
审稿时长
4-8 weeks
期刊介绍: Pediatric Diabetes is a bi-monthly journal devoted to disseminating new knowledge relating to the epidemiology, etiology, pathogenesis, management, complications and prevention of diabetes in childhood and adolescence. The aim of the journal is to become the leading vehicle for international dissemination of research and practice relating to diabetes in youth. Papers are considered for publication based on the rigor of scientific approach, novelty, and importance for understanding mechanisms involved in the epidemiology and etiology of this disease, especially its molecular, biochemical and physiological aspects. Work relating to the clinical presentation, course, management and outcome of diabetes, including its physical and emotional sequelae, is considered. In vitro studies using animal or human tissues, whole animal and clinical studies in humans are also considered. The journal reviews full-length papers, preliminary communications with important new information, clinical reports, and reviews of major topics. Invited editorials, commentaries, and perspectives are a regular feature. The editors, based in the USA, Europe, and Australasia, maintain regular communications to assure rapid turnaround time of submitted manuscripts.
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