{"title":"麻黄素在治疗新冠肺炎中的应用。","authors":"Amin Sadeghi Dousari, Marzieh Karimian Amroabadi, Zahra Soofi Neyestani, Majid Taati Moghadam, Naghmeh Satarzadeh","doi":"10.22038/AJP.2022.21607","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong><i>Ephedra</i> herbs are the only extant genus in its family, Ephedraceae, and order, Ephedrales. It has been prescribed in traditional medicine for improving headaches and respiratory infections. On the other hand, because the coronavirus disease 2019 (COVID-19) causes respiratory problems and COVID-19 pandemic is the most widespread outbreak that has affected humanity in the last century, the current review aims using literature search to investigate the effects of the <i>Ephedra</i> herbs compounds on COVID-19 to supply a reference for its clinical application in the inhibition and remedy of COVID-19.</p><p><strong>Materials and methods: </strong>This review was performed using articles published in various databases, including Web of Science, PubMed, Scopus, and Google Scholar, without a time limit. For this paper, the following keywords were used: \"<i>Ephedra</i>\", \"coronavirus disease 2019\", \"COVID-19\", \"Severe acute respiratory syndrome coronavirus 2\" or \"SARS CoV 2\".</p><p><strong>Results: </strong>The results of this review show that the <i>Ephedra</i> herbs have effectiveness on COVID-19 and its compounds can bind to angiotensin-converting enzyme 2 (ACE2) with a high affinity and act as a blocker and prevent the binding of the virus.</p><p><strong>Conclusion: </strong>Some plants used in traditional medicine, including the <i>Ephedra</i> herbs, with their active compounds, can be considered a candidate with high potential for the control and prevention of COVID-19.</p>","PeriodicalId":8677,"journal":{"name":"Avicenna Journal of Phytomedicine","volume":null,"pages":null},"PeriodicalIF":1.9000,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10465882/pdf/","citationCount":"0","resultStr":"{\"title\":\"The use of <i>Ephedra</i> herbs in the treatment of COVID-19.\",\"authors\":\"Amin Sadeghi Dousari, Marzieh Karimian Amroabadi, Zahra Soofi Neyestani, Majid Taati Moghadam, Naghmeh Satarzadeh\",\"doi\":\"10.22038/AJP.2022.21607\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objective: </strong><i>Ephedra</i> herbs are the only extant genus in its family, Ephedraceae, and order, Ephedrales. It has been prescribed in traditional medicine for improving headaches and respiratory infections. On the other hand, because the coronavirus disease 2019 (COVID-19) causes respiratory problems and COVID-19 pandemic is the most widespread outbreak that has affected humanity in the last century, the current review aims using literature search to investigate the effects of the <i>Ephedra</i> herbs compounds on COVID-19 to supply a reference for its clinical application in the inhibition and remedy of COVID-19.</p><p><strong>Materials and methods: </strong>This review was performed using articles published in various databases, including Web of Science, PubMed, Scopus, and Google Scholar, without a time limit. For this paper, the following keywords were used: \\\"<i>Ephedra</i>\\\", \\\"coronavirus disease 2019\\\", \\\"COVID-19\\\", \\\"Severe acute respiratory syndrome coronavirus 2\\\" or \\\"SARS CoV 2\\\".</p><p><strong>Results: </strong>The results of this review show that the <i>Ephedra</i> herbs have effectiveness on COVID-19 and its compounds can bind to angiotensin-converting enzyme 2 (ACE2) with a high affinity and act as a blocker and prevent the binding of the virus.</p><p><strong>Conclusion: </strong>Some plants used in traditional medicine, including the <i>Ephedra</i> herbs, with their active compounds, can be considered a candidate with high potential for the control and prevention of COVID-19.</p>\",\"PeriodicalId\":8677,\"journal\":{\"name\":\"Avicenna Journal of Phytomedicine\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.9000,\"publicationDate\":\"2023-05-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10465882/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Avicenna Journal of Phytomedicine\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.22038/AJP.2022.21607\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"CHEMISTRY, MEDICINAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Avicenna Journal of Phytomedicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.22038/AJP.2022.21607","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CHEMISTRY, MEDICINAL","Score":null,"Total":0}
引用次数: 0
摘要
目的:麻黄属是麻黄科和麻黄目中唯一现存的属。它在传统医学中被用来改善头痛和呼吸道感染。另一方面,由于2019冠状病毒病(新冠肺炎)导致呼吸系统问题,而新冠肺炎大流行是上个世纪影响人类最广泛的疫情,本综述旨在通过文献检索研究麻黄素类草药化合物对新冠肺炎的影响,为其在抑制和治疗新冠肺炎方面的临床应用提供参考。材料和方法:本综述使用发表在各种数据库中的文章进行,包括Web of Science、PubMed、Scopus和Google Scholar,没有时间限制。本文使用了以下关键词:“麻黄碱”、“2019冠状病毒病”、“新冠肺炎”、,“严重急性呼吸综合征冠状病毒2”或“SARS冠状病毒2”。结论:一些传统医学中使用的植物,包括麻黄属植物及其活性化合物,可被认为是新冠肺炎的高潜力防治候选植物。
The use of Ephedra herbs in the treatment of COVID-19.
Objective: Ephedra herbs are the only extant genus in its family, Ephedraceae, and order, Ephedrales. It has been prescribed in traditional medicine for improving headaches and respiratory infections. On the other hand, because the coronavirus disease 2019 (COVID-19) causes respiratory problems and COVID-19 pandemic is the most widespread outbreak that has affected humanity in the last century, the current review aims using literature search to investigate the effects of the Ephedra herbs compounds on COVID-19 to supply a reference for its clinical application in the inhibition and remedy of COVID-19.
Materials and methods: This review was performed using articles published in various databases, including Web of Science, PubMed, Scopus, and Google Scholar, without a time limit. For this paper, the following keywords were used: "Ephedra", "coronavirus disease 2019", "COVID-19", "Severe acute respiratory syndrome coronavirus 2" or "SARS CoV 2".
Results: The results of this review show that the Ephedra herbs have effectiveness on COVID-19 and its compounds can bind to angiotensin-converting enzyme 2 (ACE2) with a high affinity and act as a blocker and prevent the binding of the virus.
Conclusion: Some plants used in traditional medicine, including the Ephedra herbs, with their active compounds, can be considered a candidate with high potential for the control and prevention of COVID-19.