Jian Zhang , Zhi-Hui Sun , Bing-Zheng Liu , Wei-Yi Su , Ya-Qing Chang
{"title":"foxl2在海胆(mesocentrrotus nudus)中的两性二态表达","authors":"Jian Zhang , Zhi-Hui Sun , Bing-Zheng Liu , Wei-Yi Su , Ya-Qing Chang","doi":"10.1016/j.gep.2022.119280","DOIUrl":null,"url":null,"abstract":"<div><p><span>Sea urchin (</span><em>Mesocentrotus nudus</em><span>) is an important economically mariculture species in several Asian countries, and gonads are the sole edible parts for people. In addition to commercial value, it is an excellent model for studying gonadal development, sex determination and sex differentiation. Identify sex-related genes is an effective way to reveal the molecular mechanism of gonadal development. In the present study, the </span><em>foxl2</em> homologous gene was identified in <em>M. nudus. Foxl2</em> is not a maternal factor, and is detected for the first time in two-arm stages. Additionally, the expression of <em>foxl2</em> in the testis is higher than in the ovaries at the same developmental stages. The <em>foxl2</em> transcripts were specifically enriched in the cytoplasm of germ cellsboth in the ovary and testis, but their proteins were more concentrated in the area near the oocyte nucleus. Overall, this study contributes to our understanding of the dynamic and sexually dimorphic expression pattern of <em>foxl2</em><span> and provide a useful germ cell marker during gametogenesis in sea urchin.</span></p></div>","PeriodicalId":55598,"journal":{"name":"Gene Expression Patterns","volume":null,"pages":null},"PeriodicalIF":1.0000,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":"{\"title\":\"Sexually dimorphic expression of foxl2 in the sea urchin (Mesocentrotus nudus)\",\"authors\":\"Jian Zhang , Zhi-Hui Sun , Bing-Zheng Liu , Wei-Yi Su , Ya-Qing Chang\",\"doi\":\"10.1016/j.gep.2022.119280\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p><span>Sea urchin (</span><em>Mesocentrotus nudus</em><span>) is an important economically mariculture species in several Asian countries, and gonads are the sole edible parts for people. In addition to commercial value, it is an excellent model for studying gonadal development, sex determination and sex differentiation. Identify sex-related genes is an effective way to reveal the molecular mechanism of gonadal development. In the present study, the </span><em>foxl2</em> homologous gene was identified in <em>M. nudus. Foxl2</em> is not a maternal factor, and is detected for the first time in two-arm stages. Additionally, the expression of <em>foxl2</em> in the testis is higher than in the ovaries at the same developmental stages. The <em>foxl2</em> transcripts were specifically enriched in the cytoplasm of germ cellsboth in the ovary and testis, but their proteins were more concentrated in the area near the oocyte nucleus. Overall, this study contributes to our understanding of the dynamic and sexually dimorphic expression pattern of <em>foxl2</em><span> and provide a useful germ cell marker during gametogenesis in sea urchin.</span></p></div>\",\"PeriodicalId\":55598,\"journal\":{\"name\":\"Gene Expression Patterns\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.0000,\"publicationDate\":\"2022-12-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"2\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Gene Expression Patterns\",\"FirstCategoryId\":\"99\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S1567133X22000503\",\"RegionNum\":4,\"RegionCategory\":\"生物学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"DEVELOPMENTAL BIOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Gene Expression Patterns","FirstCategoryId":"99","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1567133X22000503","RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"DEVELOPMENTAL BIOLOGY","Score":null,"Total":0}
Sexually dimorphic expression of foxl2 in the sea urchin (Mesocentrotus nudus)
Sea urchin (Mesocentrotus nudus) is an important economically mariculture species in several Asian countries, and gonads are the sole edible parts for people. In addition to commercial value, it is an excellent model for studying gonadal development, sex determination and sex differentiation. Identify sex-related genes is an effective way to reveal the molecular mechanism of gonadal development. In the present study, the foxl2 homologous gene was identified in M. nudus. Foxl2 is not a maternal factor, and is detected for the first time in two-arm stages. Additionally, the expression of foxl2 in the testis is higher than in the ovaries at the same developmental stages. The foxl2 transcripts were specifically enriched in the cytoplasm of germ cellsboth in the ovary and testis, but their proteins were more concentrated in the area near the oocyte nucleus. Overall, this study contributes to our understanding of the dynamic and sexually dimorphic expression pattern of foxl2 and provide a useful germ cell marker during gametogenesis in sea urchin.
期刊介绍：
Gene Expression Patterns is devoted to the rapid publication of high quality studies of gene expression in development. Studies using cell culture are also suitable if clearly relevant to development, e.g., analysis of key regulatory genes or of gene sets in the maintenance or differentiation of stem cells. Key areas of interest include:
-In-situ studies such as expression patterns of important or interesting genes at all levels, including transcription and protein expression
-Temporal studies of large gene sets during development
-Transgenic studies to study cell lineage in tissue formation
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