涡虫:一个多功能和强大的模型系统，用于再生，成体干细胞调节，衰老和行为的分子研究。

CSH protocols Pub Date : 2008-10-01 DOI:10.1101/pdb.emo101

Néstor J Oviedo, Cindy L Nicolas, Dany S Adams, Michael Levin

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引用次数: 37

摘要

近年来，涡虫越来越被认为是一种新兴的模式生物，适合于分子遗传技术，旨在理解在后生动物中常见的复杂生物任务。越来越多的证据表明，这种模式生物在组织再生、干细胞调节、组织更新、各种药物的药理作用、癌症和衰老的机制方面具有独特的优势。本文概述了涡虫模式系统，特别关注地中海施米德涡虫。此外，还提供了有关该生物最常用的信息，以及现代基因组资源和技术方法。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Planarians: a versatile and powerful model system for molecular studies of regeneration, adult stem cell regulation, aging, and behavior.

INTRODUCTIONIn recent years, planarians have been increasingly recognized as an emerging model organism amenable to molecular genetic techniques aimed at understanding complex biological tasks commonly observed among metazoans. Growing evidence suggests that this model organism is uniquely poised to inform us about the mechanisms of tissue regeneration, stem cell regulation, tissue turnover, pharmacological action of diverse drugs, cancer, and aging. This article provides an overview of the planarian model system with special attention to the species Schmidtea mediterranea. Additionally, information is provided about the most popular use of this organism, together with modern genomic resources and technical approaches.

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