增材制造聚醚酮支架修复大骨缺损的力学研究。

Seyed Ataollah Naghavi, Changning Sun, Mahbubeh Hejazi, Maryam Tamaddon, Jibao Zheng, Leilei Wang, Chenrui Zhang, Swastina Nath Varma, Dichen Li, Mehran Moazen, Ling Wang, Chaozong Liu, San, Cs, San, Mh, San, Mm, Lw, Cl, San, Cs, Mh, Mt, Jz, Lw, Cz, Snv, Dl, Mm, Lw, Cl
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引用次数: 10

摘要

聚醚醚酮(PEEK)是一种广泛应用于制造假体的材料,近年来随着增材制造技术的发展,PEEK材料在大型骨缺损修复中得到了广泛的关注。这是由于其优异的生物相容性,良好的热稳定性和化学稳定性以及类似的机械性能,模仿天然骨。本研究设计了3个重复的直线型支架,进行压缩、拉伸、三点弯曲和扭转试验,单胞尺寸为0.8 mm,孔隙大小为0.4 mm,支撑厚度为0.4 mm,标称孔隙率为50%。应力应变图由实验模型和有限元分析模型组成。从应力应变图斜率测得支架的试验杨氏模量和屈服强度,压缩试验分别为395和19.50 MPa,拉伸试验分别为427和6.96 MPa,三点弯曲试验分别为257和25.30 MPa,扭转试验分别为231和12.83 MPa。有限元模型与试验结果吻合较好。由于增材制造PEEK的结晶度较低,结构在拉伸应变作用下的韧性断裂是PEEK支架的主要失效模式。多孔PEEK的力学性能接近松质骨,因此有望在未来用于增材制造PEEK骨植入物,但较低的屈服强度给设计带来了挑战。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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On the mechanical aspect of additive manufactured polyether-ether-ketone scaffold for repair of large bone defects.

Polyether-ether-ketone (PEEK) is widely used in producing prosthesis and have gained great attention for repair of large bone defect in recent years with the development of additive manufacturing. This is due to its excellent biocompatibility, good heat and chemical stability and similar mechanical properties which mimics natural bone. In this study, three replicates of rectilinear scaffolds were designed for compression, tension, three-point bending and torsion test with unit cell size of 0.8 mm, a pore size of 0.4 mm, strut thickness of 0.4 mm and nominal porosity of 50%. Stress-strain graphs were developed from experimental and finite element analysis models. Experimental Young's modulus and yield strength of the scaffolds were measured from the slop of the stress-strain graph to be 395 and 19.50 MPa respectively for compression, 427 and 6.96 MPa respectively for tension, 257 and 25.30 MPa respectively for three-point bending and 231 and 12.83 MPa respectively for torsion test. The finite element model was found to be in good agreement with the experimental results. Ductile fracture of the struct subjected to tensile strain was the main failure mode of the PEEK scaffold, which stems from the low crystallinity of additive manufacturing PEEK. The mechanical properties of porous PEEK are close to those of cancellous bone and thus are expected to be used in additive manufacturing PEEK bone implants in the future, but the lower yield strength poses a design challenge.

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来源期刊
CiteScore
6.70
自引率
0.00%
发文量
9
期刊最新文献
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