尼日利亚西南部农村地区急性严重哮喘及其死亡率预测因素:一项为期五年的回顾性观察研究

IF 3.5 3区 医学 Q2 RESPIRATORY SYSTEM Chronic Respiratory Disease Pub Date : 2023-01-01 DOI:10.1177/14799731221151183
Azeez Oyemomi Ibrahim, Shuaib Kayode Aremu, Babatunde Adeola Afolabi, Gbadebo Oladimeji Ajani, Fasanmi Tolulope Kolawole, OlufunmilayoAdenike Oguntoye
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引用次数: 1

摘要

目的:观察到尼日利亚哮喘死亡率预测因素的数据缺乏。本研究旨在确定尼日利亚西南部农村急性严重哮喘死亡率的临床表现和预测因素。方法:采用回顾性观察研究,采用数据表和标准化问卷对2015年1月至2019年12月在急诊科收治的124例患者进行回顾性分析。数据分析采用SPSS Version 22.0。结果以描述性和表格形式呈现。采用二元logistic回归分析确定哮喘死亡率的预测因素并确定p值。结果:共研究了124例患者。急性重症哮喘病死率为4.8%,预测因素为年龄较大(粗优势比(COR), 14.857;95% CI: 2.489-88.696, p < .001),吸烟(COR, 6.741;95% CI: 1.170-38.826, p = 0.016),超过3例合并症(COR, 2.750;95% CI: 1.147-26.454, p = 0.012),糖尿病(COR, 13.750;95% CI: 2.380-79.433, p < 0.001),人类免疫缺陷病毒(COR, 117.000;95% CI: 9.257-1479.756, p < .001),就诊前≥2天(COR, 7.440;95% CI: 1.288-42.980, p = 0.039),短效b2激动剂过度使用(COR, 7.041;95% CI: 1.005-62.165, p = 0.044)。结论:死亡率为4.8%,预测因素为高龄患者、吸烟、多种合并症、糖尿病、HIV、SP02
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Acute severe asthma and its predictors of mortality in rural Southwestern Nigeria: a-five year retrospective observational study.

Objectives: There is an observed paucity of data regarding the predictors of asthma mortality in Nigeria. This study aimed to ascertain the clinical presentations and predictors of acute severe asthma mortality in rural Southwestern Nigeria.

Methods: A retrospective observational study using a data form and a standardized questionnaire was used to review the 124 patients admitted at Emergency Department between January 2015 and December 2019. The data were analyzed using SPSS Version 22.0. The results were presented in descriptive and tabular formats. Binary logistic regression analysis was used to determine the predictors of asthma mortality and a p-value <.05 was considered statistically significant.

Results: A total of 124 patients were studied. The acute severe asthma mortality was 4.8% and its predictors were older age (Crude odds Ratio (COR), 14.857; 95% CI: 2.489-88.696, p < .001), Tobacco smoking (COR, 6.741; 95% CI: 1.170-38.826, p = .016), more than three co-morbidities (COR, 2.750; 95% CI: 1.147-26.454, p = 0.012), diabetes mellitus (COR, 13.750; 95% CI: 2.380-79.433, p < .001), Human Immunodeficiency virus (COR, 117.000; 95% CI: 9.257-1479.756, p < .001), ≥2 days before presentation (COR, 7.440; 95% CI: 1.288-42.980, p = .039), and Short-acting-B2-agonists overuse (COR, 7.041; 95% CI: 1.005-62.165, p = .044).

Conclusion: The mortality rate was 4.8% and its predictors were older age patients, tobacco smoking, multiple co-morbidities, diabetes mellitus, HIV, SP02 <90%, delay presentation, and Short-acting-B2-agonists over use, The study showed that there is high prevalence of asthma mortality in rural Southwestern Nigeria. The findings may be used to plan for asthma preventions and control programs in rural settings, and may also provide an impetus for prospective research on these outcomes.

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来源期刊
Chronic Respiratory Disease
Chronic Respiratory Disease RESPIRATORY SYSTEM-
CiteScore
5.90
自引率
7.30%
发文量
47
审稿时长
11 weeks
期刊介绍: Chronic Respiratory Disease is a peer-reviewed, open access, scholarly journal, created in response to the rising incidence of chronic respiratory diseases worldwide. It publishes high quality research papers and original articles that have immediate relevance to clinical practice and its multi-disciplinary perspective reflects the nature of modern treatment. The journal provides a high quality, multi-disciplinary focus for the publication of original papers, reviews and commentary in the broad area of chronic respiratory disease, particularly its treatment and management.
期刊最新文献
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