青少年和成人主动脉缩窄支架:单中心经验。

IF 0.7 4区 医学 Q4 PERIPHERAL VASCULAR DISEASE Vascular and Endovascular Surgery Pub Date : 2023-11-01 Epub Date: 2023-06-10 DOI:10.1177/15385744231183476
Arnaud Colle, Stéphane Kajingu Enciso, Louise Brunee, Thierry Sluysmans, Joëlle Kefer, Parla Astarci, Valerie Lacroix, Maxime Elens
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引用次数: 0

摘要

目的/背景:本研究的目的是评估青少年和成年人群主动脉缩窄(AoCo)支架植入的短期和中期结果。方法:本研究纳入了2000年12月至2016年11月期间接受支架置入治疗的所有年龄超过14岁的AoCo患者。确定了28名侵入性峰值收缩压梯度>20mmHg的患者。评估放射次数、无创收缩压、峰值收缩压梯度、降压药物摄入、跛行状态和并发症。结果:成功放置了22个覆膜支架和6个非覆膜支架。峰值收缩压梯度在支架植入后立即从平均32毫米汞柱下降到0毫米汞柱(±7毫米汞柱)。主动脉瓣平均直径从8毫米增加到16毫米(±4毫米)。外周动脉损伤2例(7.1%),平均随访时间60±49个月。4名患者需要对支架进行重新切割,其中2名用于适应生长,2名用于再狭窄。6名(35%)患者可以停止所有降压药物治疗。所有claudicants(6/28)在手术后和随访期间均无症状。未发现动脉瘤、支架骨折或夹层。在第一次手术中有2次支架移位,只有1次需要额外放置支架。结论:主动脉缩窄支架置入术是一种安全有效的治疗方法,可显著降低峰值收缩压梯度。可以减少抗高血压药物的使用,增加跛行者的步行距离。年轻患者可能需要更频繁的再干预以适应生长。
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Aortic Coarctation Stenting in Adolescents and Adults: A Single-Center Experience.

Purpose/background: The aim of this study was to evaluate the short and midterm results of aortic coarctation (AoCo) stenting in an adolescent and adult population.

Methods: All patients with a AoCo older than 14 years treated by stent placement between December 2000 and November 2016 were included in this study. Twenty-eight patients with an invasive peak systolic pressure gradient >20 mmHg were identified. Number of redilations, non-invasive systolic blood pressure, peak systolic pressure gradient, antihypertensive medication intake, claudication status and complications were evaluated.

Results: Twenty-two covered and 6 uncovered stents were successfully placed. Peak systolic pressure gradient decreased immediately after stenting from a mean of 32 mmHg to 0 mmHg (± 7 mmHg). Mean AoCo diameter increased from 8 tot 16 mm (± 4 mm). Peripheral arterial injury was seen in 2 patients (7.1%). The mean follow-up time was 60 ± 49 months. Redilation of the stent was required in 4 patients, 2 to accommodate for growth and 2 for restenosis. Six (35%) patients could stop all antihypertensive medication. All claudicants (6/28) became and remained asymptomatic after surgery and during their follow-up. No aneurysms, stent fractures or dissections were noticed. There were 2 stent migrations during the first procedure with only 1 needing additional stent placement.

Conclusion: Aortic coarctation stenting is a safe and effective treatment that significantly reduces the peak systolic pressure gradient. Antihypertensive medication can be reduced, and increase of walking distance in claudicants can be obtained. Younger patients may need more frequent reinterventions to accommodate for growth.

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来源期刊
Vascular and Endovascular Surgery
Vascular and Endovascular Surgery SURGERY-PERIPHERAL VASCULAR DISEASE
CiteScore
1.70
自引率
11.10%
发文量
132
审稿时长
4-8 weeks
期刊介绍: Vascular and Endovascular Surgery (VES) is a peer-reviewed journal that publishes information to guide vascular specialists in endovascular, surgical, and medical treatment of vascular disease. VES contains original scientific articles on vascular intervention, including new endovascular therapies for peripheral artery, aneurysm, carotid, and venous conditions. This journal is a member of the Committee on Publication Ethics (COPE).
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