利用RT-qPCR技术筛查血液肿瘤化疗患者的SARS-COV-2

Q4 Biochemistry, Genetics and Molecular Biology Prague medical report Pub Date : 2023-01-01 DOI:10.14712/23362936.2023.3
Ignacio Martín Santarelli, Mariela Sierra, Sofía Isabel Fernández
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引用次数: 0

摘要

鉴于白血病和淋巴瘤患者患重症COVID-19的风险很高,建议在每次治疗前使用RT-qPCR对其进行SARS-COV-2普遍筛查。这与优先检测有症状患者的不同建议产生了冲突。我们发现,在化疗前无症状的血液肿瘤患者中获得的56例RT-qPCR中,2例(3.5%)为阳性。阴性结果不排除1例患者(1.8%)感染SARS-COV-2。目前尚不清楚在接受化疗的血液肿瘤患者中使用RT-qPCR筛查SARS-COV-2的好处是什么。
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Screening for SARS-COV-2 Using RT-qPCR in Patients with Hematologic Neoplasms Receiving Chemotherapy.

It has been recommended that patients with leukaemias and lymphomas undergo universal screening for SARS-COV-2 using RT-qPCR before each treatment on the grounds of their high risk of experiencing severe forms of COVID-19. This raises a conflict with different recommendations which prioritise testing symptomatic patients. We found that among 56 RT-qPCR obtained in asymptomatic patients with hematologic neoplasms before chemotherapy administration, 2 (3.5%) were positive. A negative result did not exclude SARS-COV-2 infection in 1 patient (1.8%). It is unclear what the benefit of screening for SARS-COV-2 using RT-qPCR in patients with hematologic neoplasms who receive chemotherapy is.

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来源期刊
Prague medical report
Prague medical report Medicine-Medicine (all)
CiteScore
1.10
自引率
0.00%
发文量
19
审稿时长
20 weeks
期刊最新文献
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