保留瓣膜的主动脉根置换技术:Valsalva移植物与两根直管移植物。

IF 1.8 4区 医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS Cardiology Research and Practice Pub Date : 2023-01-01 DOI:10.1155/2023/4076881
Alexander Makkinejad, Bailey Brown, Rana-Armaghan Ahmad, Joanna Hua, Xiaoting Wu, Shinichi Fukuhara, Karen Kim, Himanshu Patel, G Michael Deeb, Bo Yang
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引用次数: 0

摘要

背景:保留瓣膜的主动脉根部置换术有很多不同的方法。我们的目的是确定移植物对中期结果的影响:Valsalva移植物与两个直管移植物。方法:2004年至2020年,332例患者采用Valsalva移植物(Valsalva组:n = 270)或两个直管移植物(两个移植物组:n = 62)进行保留瓣膜的主动脉根置换术。数据通过图表审查和国家死亡指数获得。主要结局为中期生存和免于再手术。结果:两组术前特征相似,但两组有更多的A型夹层(32%比19%)和紧急手术(26%比15%),年龄更年轻(45比50岁)。术中,两组相似,但两组的交叉钳夹时间(245分钟对215分钟)和体外循环时间(284分钟对255分钟)更长。术后并发症包括出血再手术、卒中、起搏器植入和肾功能衰竭在Valsalva组稍高,但差异不显著。Valsalva组和双移植组的手术死亡率相似(0.7% vs 0%)。双移植组的5年生存率为100%,而Valsalva组为96% (p=0.56)。两组5年再手术自由度为100%,而Valsalva组为93% (p=0.29)。结论:Valsalva技术和双瓣移植技术均具有良好的中短期疗效。双移植物技术可能有稍好的存活率和免于再次手术的自由,但需要更大的样本量和更长的随访时间来确定这些优势是否显著。
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Valve-Sparing Aortic Root Replacement Technique: Valsalva Graft versus Two Straight Tubular Grafts.

Background: There are many variations in valve-sparing aortic root replacement techniques. Our aim is to determine the impact of the graft on mid-term outcomes: Valsalva graft vs. two straight tubular grafts.

Methods: From 2004 to 2020, 332 patients underwent valve-sparing aortic root replacement with either a Valsalva graft (Valsalva group: n = 270) or two straight tubular grafts (two-graft group: n = 62). Data were obtained through chart review and the National Death Index. Primary outcomes were mid-term survival and freedom from reoperation.

Results: The preoperative characteristics of the groups were similar, but the two-graft group had more type A dissections (32% vs. 19%) and emergent operations (26% vs. 15%) and was younger (45 vs. 50 years). Intraoperatively, the groups were similar, but the two-graft group had longer cross-clamp (245 vs. 215 minutes) and cardiopulmonary bypass times (284 vs. 255 minutes). Postoperative complications including reoperation for bleeding, stroke, pacemaker implantation, and renal failure were slightly more frequent in the Valsalva group, but the differences were not significant. Operative mortality was similar between the Valsalva and two-graft groups (0.7% vs. 0%). Five-year survival in the two-graft group was 100% compared to 96% in the Valsalva group (p=0.56). Five-year freedom from reoperation in the two-graft group was 100% compared to 93% in the Valsalva group (p=0.29).

Conclusions: The Valsalva and two-graft techniques both have excellent short- and mid-term outcomes. The two-graft technique might have slightly better survival and freedom from reoperation, but a larger sample size and longer follow-up are needed to determine if these advantages are significant.

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来源期刊
Cardiology Research and Practice
Cardiology Research and Practice Medicine-Cardiology and Cardiovascular Medicine
CiteScore
4.40
自引率
0.00%
发文量
64
审稿时长
13 weeks
期刊介绍: Cardiology Research and Practice is a peer-reviewed, Open Access journal that publishes original research articles, review articles, and clinical studies that focus on the diagnosis and treatment of cardiovascular disease. The journal welcomes submissions related to systemic hypertension, arrhythmia, congestive heart failure, valvular heart disease, vascular disease, congenital heart disease, and cardiomyopathy.
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