黑加仑和覆盆子食用对血压的影响:随机对照试验的系统回顾和荟萃分析。

Ali Nikparast, Fatemeh Sheikhhossein, Mohammad Reza Amini, Sogand Tavakoli, Azita Hekmatdoost
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引用次数: 1

摘要

系统回顾和荟萃分析旨在总结有关覆盆子和黑醋栗食用对血压(BP)影响的研究。通过检索PubMed、Scopus、Web of Science、Cochrane Library和Google Scholar等5个在线数据库,直到2022年12月17日,才发现符合条件的研究。我们通过应用随机效应模型合并了均值差及其95%置信区间(CI)。总的来说,覆盆子和黑加仑对BP的影响在10项随机对照试验(rct)(420名受试者)中被报道。6项临床试验的汇总分析显示,食用覆盆子没有显著降低收缩压(SBP)(加权平均差异[wmd], -1.42;95% CI, -3.27 ~ 0.87;p = 0.224)和舒张压(DBP) (WMD, -0.53;95% CI, -1.77 ~ 0.71;P = 0.401),与安慰剂相比。此外,四项临床试验的汇总分析表明,食用黑加仑并不能降低收缩压(WMD, -1.46;95% CI, -6.62 ~ 3.7;p = 0.579), DBP (WMD, -2.09;95% CI, -4.38 ~ 0.20;P = 0.07)。覆盆子和黑醋栗的摄入没有引起血压的显著降低。需要更准确的随机对照试验来阐明覆盆子和黑醋栗摄入对血压的影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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The Effects of Blackcurrant and Raspberry Consumption on Blood Pressure: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

A systematic review and meta-analysis were designed to summarize studies conducted on the effects of raspberry and blackcurrant consumption on blood pressure (BP). Eligible studies were detected by searching numerous five online databases including PubMed, Scopus, Web of Science, Cochrane Library, and Google Scholar, until December 17, 2022. We pooled the mean difference and its 95% confidence interval (CI) by applying a random-effects model. Overall, the impact of raspberry and blackcurrant on BP was reported in ten randomized controlled trials (RCTs) (420 subjects). Pooled analysis of six clinical trials revealed that raspberry consumption has no significant reduction in systolic blood pressure (SBP) (weighted mean differences [WMDs], -1.42; 95% CI, -3.27 to 0.87; p = 0.224) and diastolic blood pressure (DBP) (WMD, -0.53; 95% CI, -1.77 to 0.71; p = 0.401), in comparison with placebo. Moreover, pooled analysis of four clinical trials indicated that blackcurrant consumption did not reduce SBP (WMD, -1.46; 95% CI, -6.62 to 3.7; p = 0.579), and DBP (WMD, -2.09; 95% CI, -4.38 to 0.20; p = 0.07). Raspberry and blackcurrant consumption elicited no significant reductions in BP. More accurate RCTs are required to clarify the impact of raspberry and blackcurrant intake on BP.

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