从地面跌落的高出血风险老年病人死亡率的早期风险分层:全国数据分析。

Nasim Ahmed, Yen-Hong Kuo
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摘要

背景:本研究的目的是确定有抗凝剂使用史或凝血病史并发生地面跌倒(GLF)的患者早期死亡的风险因素:本研究的目的是确定有使用抗凝剂或凝血病史且发生地面摔倒(GLF)的患者早期死亡的风险因素:研究访问了美国外科学院创伤质量改进计划(ACS-TQIP)2013至2016日历年的数据集。所有年龄≥65岁、服用抗凝血剂并发生GLF的老年患者均纳入研究。患者的其他特征包括:性别、种族、初始收缩压(SBP)、低血压(SBP 低于 110 mmHg)、损伤严重程度评分(ISS)、格拉斯哥昏迷量表(GCS)评分、合并症,如高血压(HTN)、充血性心力衰竭(CHF)、慢性肾功能衰竭(CRF)、慢性肺阻塞性疾病(COPD)和肝硬化。为建立风险模型进行了多变量分析:共有 10,368 名患者符合研究条件。结果:共有 10,368 名患者符合研究条件,其中 788 名(7.6%)患者死亡。患者年龄的中位数[IQR]为80 [75-85]岁。90%以上的患者为白人。54%的患者为女性。约 8% 的患者在入院时出现低血压。多变量分析显示,高龄、男性、高ISS、低GCS、低血压、CHF、CRF、COPD和肝硬化对死亡率的影响非常显著:结论:约有8%服用抗凝剂或有凝血病史的GLF患者死亡。某些人口统计学特征、较高的损伤严重程度和一些合并症与院内死亡率高度相关。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Early risk stratification of mortality in the geriatric patients who are at high risk for bleeding and fall from a ground level: an analysis of the national data.

Background: The purpose of the study is to identify the risk factors of mortality early in patients who have history of using of anticoagulants or coagulopathy and sustained a ground level fall (GLF).

Methods: The American College of Surgeons Trauma Quality Improvement Program (ACS-TQIP) dataset of the calendar year 2013 through 2016 was accessed for the study. All elderly patients ≥ 65 years old, who were taking an anticoagulant and suffered from a GLF, were included in the study. Other patient characteristics included: sex, race, initial systolic blood pressure (SBP), hypotension (SBP less than 110 mmHg), Injury Severity Score (ISS), Glasgow Coma Scale (GCS) Score, comorbidities such as hypertension (HTN), congestive heart failure (CHF), chronic renal failure (CRF), chronic pulmonary obstructive disease (COPD) and cirrhosis. Multivariable analysis was performed to develop the risk model.

Results: A total of 10,368 patients qualified for the study. Of this total, 788 (7.6%) patients died. The median [IQR] age of the patients was 80 [75-85] years. More than 90% of the patients were white. Fifty-four percent of the patients were female. Approximately 8% of the patients presented with hypotension at the time of hospital arrival. Multivariable analysis showed advanced age, male gender, high ISS, low GCS, presence of hypotension, CHF, CRF, COPD and cirrhosis were highly significant for odds of mortality.

Conclusions: Approximately 8% of the patients, who took an anticoagulant or had a history of coagulopathy and sustained a GLF, died. Certain demographics, higher injury severity and a few comorbidities were highly associated with in-hospital mortality.

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