估计成人脊柱畸形手术后脊柱骨盆并发症的成本。

IF 2.1 Q3 HEALTH CARE SCIENCES & SERVICES ClinicoEconomics and Outcomes Research Pub Date : 2023-11-09 eCollection Date: 2023-01-01 DOI:10.2147/CEOR.S437202
Scott L Zuckerman, Daniel Cher, Robyn Capobianco, Daniel Sciubba, David W Polly
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引用次数: 0

摘要

目的:成人脊柱畸形(ASD)术后再手术治疗脊柱盆腔衰竭较为常见。我们试图确定因脊柱骨盆构造失败而再次手术的ASD手术的额外费用。方法:构建马尔可夫过程模型,计算ASD术后椎盂构造失败的5年折现成本。全国住院患者样本(NIS)被询问以估计ASD手术的数量。模型输入基于文献综述和专家意见。ASD手术定义为4节段或以上胸腰椎融合伴骨盆固定。以下盆腔固定失败包括:1)L4-S1棒骨折或假关节,2)髂螺钉失败或固定塞脱位,3)髂螺钉突出,4)骶髂关节疼痛。美国每年接受自闭症谱系障碍手术的患者数量是通过商业索赔数据库确定的。结果:每位患者脊柱骨盆并发症的净现值5年成本为35,265美元,相当于指数手术成本的29%。鉴于美国每年估计有27580例脊柱骨盆并发症,治疗脊柱骨盆并发症的额外费用在5年内达到近10亿美元。敏感性分析显示,这些费用对棒骨折/假关节、髂螺钉突出和再手术的发生率最为敏感。结论:保守估计ASD手术后脊柱骨盆衰竭的成本是可观的,在5年内接近10亿美元。我们提出了一种捕获脊柱骨盆固定失败的方法,用于未来的临床研究和成本分析。
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Estimating the Cost of Spinopelvic Complications After Adult Spinal Deformity Surgery.

Objective: Reoperations for spinopelvic failure after adult spinal deformity (ASD) surgery are common. We sought to determine the added costs of ASD surgery attributable to reoperations for spinopelvic construct failures.

Methods: We constructed a Markov process model to calculate the expected discounted 5-year costs of spinopelvic construct failures after ASD surgery. The Nationwide Inpatient Sample (NIS) was queried to estimate the number of ASD surgeries. Model inputs were based on literature review and expert opinion. ASD surgery was defined as thoracolumbar fusion of 4 or more levels with pelvic fixation. The following pelvic fixation failures were included: 1) rod fracture or pseudarthrosis from L4-S1, 2) iliac screw failure or set plug dislodgment, 3) iliac screw prominence, and 4) sacroiliac (SI) joint pain. The number of patients undergoing ASD surgery annually in the US was determined using a commercial claims database.

Results: The net present value 5-year cost per patient for spinopelvic complications was $35,265, equal to 29% of index surgery costs. Given an estimated 27,580 cases annually in the US, the additional cost to address spinopelvic complications reach nearly $1 billion over 5-years. A sensitivity analysis showed that these costs were most sensitive to the rate of rod fracture/pseudarthrosis, iliac screw prominence, and reoperation.

Conclusion: A conservative estimate of the cost of spinopelvic failures after ASD surgery is substantial, nearly $1 billion over 5-years. We propose a method of capturing spinopelvic fixation failures for use in future clinical studies and cost analyses.

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来源期刊
ClinicoEconomics and Outcomes Research
ClinicoEconomics and Outcomes Research HEALTH CARE SCIENCES & SERVICES-
CiteScore
3.70
自引率
0.00%
发文量
83
审稿时长
16 weeks
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