Yadessa Tegene, Selamawit Mengesha, Erin Putman, Alemayehu Toma, Mark Spigt
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Patients without hypertension or diabetes were followed for two years to determine the incidence of developing comorbidities. Nine trained nurses used a pre-tested structured questionnaire to collect data during routine care consultations in three hospitals in southern Ethiopia. To find predictors of these chronic comorbidities, a multivariable logistic regression analysis was used.</p><p><strong>Results: </strong>After two years, 54 out of 377 participants, or 14%, had chronic comorbidity, which is defined as having diabetes and/or hypertension. Hypertension (12%) and diabetes (4%), respectively, were observed. When compared to those who were not overweight, the risk of developing chronic comorbidity was three times higher in overweight people [AOR = 3.45, 95% CI: (1.04, 11.45), P = 0.045]. Older participants were about 6 times more likely than younger participants to have chronic comorbidity [AOR = 4.93, 95% CI: (1.56, 15.57), P = 0.007]. Those who did not engage in regular physical activity were twice as likely to develop chronic comorbidity [AOR = 2.16, 95% CI: (1.09, 4.29), P = 0.027].</p><p><strong>Conclusion: </strong>The incidence of chronic comorbidity was high in the study population. Targeted screening for early signs of chronic comorbidity, nutritional counseling, and awareness creation in regular physical activity programs should be integrated into HIV care to prevent and control chronic comorbidity in resource-limited settings.</p>","PeriodicalId":46555,"journal":{"name":"HIV AIDS-Research and Palliative Care","volume":"15 ","pages":"41-51"},"PeriodicalIF":1.5000,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/c0/26/hiv-15-41.PMC9940654.pdf","citationCount":"0","resultStr":"{\"title\":\"Development of Hypertension and Diabetes Mellitus, and Associated Factors, Among Adult HIV Patients in Ethiopia.\",\"authors\":\"Yadessa Tegene, Selamawit Mengesha, Erin Putman, Alemayehu Toma, Mark Spigt\",\"doi\":\"10.2147/HIV.S397511\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Medical improvements and increased access to treatment have turned HIV from a highly fatal disease into a treatable and controllable disease. With the improvement in lifespan, HIV patients face increasing morbidity and mortality from chronic comorbidities (hypertension and diabetes mellitus). There is, nevertheless, a paucity of information on the scale of HIV noncommunicable disease comorbidity and its associated factors. This study aimed to investigate the incidence and predictors of chronic comorbidity in HIV patients in a resource-limited setting.</p><p><strong>Methods: </strong>A prospective cohort study was conducted from 2019 to 2021. We included 520 HIV patients at baseline. Patients without hypertension or diabetes were followed for two years to determine the incidence of developing comorbidities. Nine trained nurses used a pre-tested structured questionnaire to collect data during routine care consultations in three hospitals in southern Ethiopia. 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引用次数: 0
摘要
背景:医疗进步和治疗机会的增加使艾滋病毒从一种高度致命的疾病转变为一种可治疗和可控的疾病。随着寿命的延长,HIV患者面临慢性合并症(高血压和糖尿病)的发病率和死亡率增加。然而,缺乏关于艾滋病毒非传染性疾病合并症的规模及其相关因素的信息。本研究旨在调查资源有限的HIV患者慢性合并症的发生率和预测因素。方法:2019 - 2021年进行前瞻性队列研究。我们纳入了520名艾滋病患者作为基线。无高血压或糖尿病的患者随访两年,以确定并发疾病的发生率。在埃塞俄比亚南部的三家医院,九名训练有素的护士在常规护理咨询期间使用预先测试的结构化问卷收集数据。为了找到这些慢性合并症的预测因素,我们使用了多变量logistic回归分析。结果:两年后,377名参与者中有54人(14%)患有慢性合并症,即糖尿病和/或高血压。分别观察到高血压(12%)和糖尿病(4%)。与非超重人群相比,超重人群发生慢性合并症的风险是非超重人群的3倍[AOR = 3.45, 95% CI: (1.04, 11.45), P = 0.045]。老年参与者患慢性合并症的可能性约为年轻参与者的6倍[AOR = 4.93, 95% CI: (1.56, 15.57), P = 0.007]。不定期进行体育锻炼的患者发生慢性合并症的可能性是前者的两倍[AOR = 2.16, 95% CI: (1.09, 4.29), P = 0.027]。结论:研究人群中慢性合并症的发生率较高。针对慢性合并症的早期症状进行有针对性的筛查、进行营养咨询以及在常规体育活动项目中提高认识,应纳入艾滋病毒护理,以在资源有限的环境中预防和控制慢性合并症。
Development of Hypertension and Diabetes Mellitus, and Associated Factors, Among Adult HIV Patients in Ethiopia.
Background: Medical improvements and increased access to treatment have turned HIV from a highly fatal disease into a treatable and controllable disease. With the improvement in lifespan, HIV patients face increasing morbidity and mortality from chronic comorbidities (hypertension and diabetes mellitus). There is, nevertheless, a paucity of information on the scale of HIV noncommunicable disease comorbidity and its associated factors. This study aimed to investigate the incidence and predictors of chronic comorbidity in HIV patients in a resource-limited setting.
Methods: A prospective cohort study was conducted from 2019 to 2021. We included 520 HIV patients at baseline. Patients without hypertension or diabetes were followed for two years to determine the incidence of developing comorbidities. Nine trained nurses used a pre-tested structured questionnaire to collect data during routine care consultations in three hospitals in southern Ethiopia. To find predictors of these chronic comorbidities, a multivariable logistic regression analysis was used.
Results: After two years, 54 out of 377 participants, or 14%, had chronic comorbidity, which is defined as having diabetes and/or hypertension. Hypertension (12%) and diabetes (4%), respectively, were observed. When compared to those who were not overweight, the risk of developing chronic comorbidity was three times higher in overweight people [AOR = 3.45, 95% CI: (1.04, 11.45), P = 0.045]. Older participants were about 6 times more likely than younger participants to have chronic comorbidity [AOR = 4.93, 95% CI: (1.56, 15.57), P = 0.007]. Those who did not engage in regular physical activity were twice as likely to develop chronic comorbidity [AOR = 2.16, 95% CI: (1.09, 4.29), P = 0.027].
Conclusion: The incidence of chronic comorbidity was high in the study population. Targeted screening for early signs of chronic comorbidity, nutritional counseling, and awareness creation in regular physical activity programs should be integrated into HIV care to prevent and control chronic comorbidity in resource-limited settings.
期刊介绍:
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