小脑后下动脉夹层导致延髓梗死,旁边形成一个巨大的纺锤形动脉瘤。

IF 1.2 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL Journal of Nippon Medical School Pub Date : 2024-03-09 Epub Date: 2023-02-21 DOI:10.1272/jnms.JNMS.2024_91-101
Masahiro Yamaguchi, Kyongsong Kim, Takayuki Mizunari, Katsuya Umeoka, Kenta Koketsu, Koshiro Isayama, Akio Morita
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引用次数: 0

摘要

小脑后下动脉(PICA)梗塞可导致延髓外侧缺血性中风。小脑后下动脉(PICA)夹层也可引起该区域的缺血性事件,但由于该血管直径较小,很难在放射影像上发现。我们报告了一名因 PICA 夹层导致瓦伦贝里综合征的 48 岁男性患者,首次入院时很难确诊。他报告说突然出现右侧面部感觉障碍、共济失调步态和头痛。脑磁共振成像(MRI)显示,右侧延髓有一处新鲜脑梗塞。入院时进行的连续磁共振成像和磁共振血管造影(MRA)均未显示脑血管异常。发病 18 个月后进行的核磁共振成像检查发现,PICA 外侧延髓段上有一个纺锤形动脉瘤;其位置与脑梗塞极为接近。我们断定脑梗塞是由 PICA 夹层引起的,因为患者在发病时突然出现症状,而且病变扩大的夹层动脉瘤与 Wallenberg 综合征的症状相吻合。动脉瘤被夹住,并放置了枕动脉-PICA 旁路。首次入院时的影像学检查结果显示,这名瓦伦贝里综合征患者的枕动脉-中动脉夹层完好无损,但在症状出现时进行的影像学检查却发现了夹层,后来才确诊为瓦伦贝里综合征。然而,18 个月后,核磁共振成像显示夹层部位的动脉瘤增大。头痛患者PICA区域的脑梗塞可能是PICA夹层的征兆。
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Formation of a Large Fusiform Aneurysm near a Medullary Infarction Caused by Dissection of the Posterior Inferior Cerebellar Artery.

Infarction of the posterior inferior cerebellar artery (PICA) can lead to ischemic stroke in the lateral medullary oblongata. PICA dissection can also elicit an ischemic event in this region, but its detection on radiological images is difficult because of the small diameter of the vessel. We report a case of Wallenberg syndrome due to PICA dissection in a 48-year-old man, which was difficult to diagnose on first admission. He reported sudden onset of sensory disturbance on the right side of his face, ataxic gait, and headache. Brain magnetic resonance imaging (MRI) revealed a fresh cerebral infarct in the right lateral medulla oblongata. Magnetic resonance angiography (MRA) performed at the time of his admission showed no cerebral vessel abnormalities. An MRI study 18 months after the event revealed a fusiform aneurysm on the lateral medullary segment of the PICA, which was extremely close to the cerebral infarct. We concluded that the infarct was due to PICA dissection because of the sudden onset of symptoms and because the infarcted territory of the occluded penetrating branch of the dissecting aneurysm was consistent with Wallenberg syndrome. The aneurysm was trapped and an occipital artery-PICA bypass was placed. At the latest follow-up, 1 year after the procedure, he had no neurological symptoms. Imaging findings at the time of his first admission indicated that the PICA was intact. However, 18 months later, MRI revealed enlargement of an aneurysm at the site of the dissection. A cerebral infarct with headache may indicate PICA dissection.

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来源期刊
Journal of Nippon Medical School
Journal of Nippon Medical School MEDICINE, GENERAL & INTERNAL-
CiteScore
1.80
自引率
10.00%
发文量
118
期刊介绍: The international effort to understand, treat and control disease involve clinicians and researchers from many medical and biological science disciplines. The Journal of Nippon Medical School (JNMS) is the official journal of the Medical Association of Nippon Medical School and is dedicated to furthering international exchange of medical science experience and opinion. It provides an international forum for researchers in the fields of bascic and clinical medicine to introduce, discuss and exchange thier novel achievements in biomedical science and a platform for the worldwide dissemination and steering of biomedical knowledge for the benefit of human health and welfare. Properly reasoned discussions disciplined by appropriate references to existing bodies of knowledge or aimed at motivating the creation of such knowledge is the aim of the journal.
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