有序响应模型中响应类别的数量。

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2022-11-01 DOI:10.1515/ijb-2021-0013
Maria Iannario, Anna Clara Monti, Pietro Scalera
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引用次数: 6

摘要

在对连续响应进行分类时,选择m个响应类别是一个至关重要的问题。本文利用了比例概率模型的特性,该特性允许从相同的潜在变量生成具有不同数量类别的有序响应。研究了m变化时回归系数估计量的渐近效率和推导出的推理过程的准确性。该分析基于具有封闭形式信息矩阵的模型,因此可以在不需要模拟的情况下解析计算渐近效率。本文证明了更精细的分类增加了数据的信息内容,从而表明回归系数的检验的渐近效率和能力随着m的增加而增加。还考虑了合并类别产生的信息损失对估计器效率的影响,突出了其风险,特别是在极端形式的二分类中进行时。此外,探讨了不同样本量下m的合适值,指出大量的类别可以通过更好的数据质量抵消小样本的有限信息量。最后,基于离散连续尺度的两个关于化疗患者生活质量和疼痛感知的案例研究说明了本文的主要发现。
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The number of response categories in ordered response models.

The choice of the number m of response categories is a crucial issue in categorization of a continuous response. The paper exploits the Proportional Odds Models' property which allows to generate ordinal responses with a different number of categories from the same underlying variable. It investigates the asymptotic efficiency of the estimators of the regression coefficients and the accuracy of the derived inferential procedures when m varies. The analysis is based on models with closed-form information matrices so that the asymptotic efficiency can be analytically evaluated without need of simulations. The paper proves that a finer categorization augments the information content of the data and consequently shows that the asymptotic efficiency and the power of the tests on the regression coefficients increase with m. The impact of the loss of information produced by merging categories on the efficiency of the estimators is also considered, highlighting its risks especially when performed in its extreme form of dichotomization. Furthermore, the appropriate value of m for various sample sizes is explored, pointing out that a large number of categories can offset the limited amount of information of a small sample by a better quality of the data. Finally, two case studies on the quality of life of chemotherapy patients and on the perception of pain, based on discretized continuous scales, illustrate the main findings of the paper.

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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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