对极度钙化或先前扩张失败的动脉进行旋转动脉粥样硬化切除术:经皮冠状动脉介入治疗后的技术方面和晚期结果

Pedro Henrique Magalhães Craveiro de Melo, Breno de Alencar Araripe Falcão, Cristiano Guedes Bezerra, Fábio Augusto Pinton, Welingson V.N. Guimarães, Rafael Cavalcante Silva, Celso K. Takimura, Marco Antônio Perin, Expedito Eustáquio Ribeiro da Silva, Antonio Esteves-Filho, José Mariani Jr., Pedro Alves Lemos Neto
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引用次数: 0

摘要

背景:在支架植入前,已经提出了旋转动脉粥样硬化切除术和新的消融策略来治疗高度钙化的病变。然而,关于在当代实践中采用这些新策略以及接受这种治疗的患者的晚期结果的数据很少。方法2012年7月至2014年11月,回顾性单中心登记,包括所有接受旋转动脉粥样硬化切除术作为治疗冠状动脉重度钙化或既往扩张失败的一部分的患者。我们评估了动脉粥样硬化切除术的技术方面和患者发生主要不良心血管事件(MACE)的晚期结局,MACE定义为死亡、q波心肌梗死或重复靶血管重建术。结果29例患者行动脉粥样硬化切除术,平均年龄69.5±7.6岁。平均毛刺与动脉之比为0.54±0.07,初始转速为161.000±13.928,动脉粥样硬化切除术后切割球囊使用率为45.1%。所有手术均取得血管造影成功。中位随访时间为13.2个月(IQ: 4.0-17.4),发生3起事件:1例非心源性死亡,2例新的靶血管重建术。平均无mace生存时间为29.7±2.1个月。结论:当代旋转动脉粥样硬化切除术采用较少侵袭性的消融策略,在后期随访中具有较高的急性成功率和较低的主要不良心血管事件发生率。
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Rotational atherectomy in arteries with extreme calcification or previous failed dilation: technical aspects and late outcomes after percutaneous coronary intervention

Background

Rotational atherectomy with new ablative strategies have been proposed for the treatment of extremely calcified lesions prior to stent implantation. Nevertheless, few data are available about the adoption of these new strategies in contemporary practice and about late outcomes of patients undergoing this therapy.

Methods

From July 2012 to November 2014, a retrospective single center registry was conducted, including all patients undergoing rotational atherectomy as part of the treatment of coronary arteries with heavy calcification or previous failed dilation. We evaluated technical aspects of atherectomy and late outcomes of patients for the occurrence of major adverse cardiovascular events (MACE), defined as death, Q-wave myocardial infarction or repeat target vessel revascularization.

Results

Twenty-nine patients with a mean age of 69.5 ± 7.6 years, underwent atherectomy. The average burr-to-artery ratio was 0.54 ± 0.07, the initial rotational speed was 161.000 ± 13.928 and the rate of cutting balloon utilization after atherectomy was 45.1%. Angiographic success was achieved in all procedures. The median follow-up time was 13.2 months (IQ: 4.0-17.4) and there were three events: 1 death of non- cardiac cause and 2 new target vessel revascularizations. The mean MACE-free survival time was 29.7 ± 2.1 months.

Conclusions

Contemporary rotational atherectomy incorporates less aggressive strategies of ablation with high rates of acute success and low occurrence of major adverse cardiovascular events during late follow-up.

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