铟(111In)标记的博来霉素用于颅内病变的检测。

Nuclear-Medizin Pub Date : 1975-08-31
M V Merrick, B Chaucer, B Clay, J P Lavender, V R McCready, M L Thakur, L H Walter
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引用次数: 0

摘要

对38名患者进行了41次脑部扫描,并与使用111铟博莱霉素后的脑部扫描结果进行了比较。他们在34对检查中得出了类似的结果,其中包括两组都未能检测到肿瘤的病例。在7个病例中,两种药物不同。在其中的两个病例中,博莱霉素比高锝酸盐更清楚地区分了开颅手术的残余肿瘤;在3例中,博莱霉素明显检测到肿瘤,而高锝酸盐未见肿瘤,在2例中,差异可能是由于技术因素,或无法解释。
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Indium (111In)-labelled bleomycin for the detection of intracranial lesions.

Brain scans with 99mTc pertechnetate were compared with scans made after administration of 111Indium bleomycin in 38 patients scanned on 41 occasions. They gave similar results in 34 pairs of examinations, including cases in which both failed to detect the tumour. In seven cases, the two agents differed. In two of these bleomycin distinguished residual tumour from the effects of craniotomy more clearly than did pertechnetate; in three bleomycin apparently detected tumour not seen with pertechnetate, and in two the differences may have been due to technical factors, or are unexplained.

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