{"title":"博来霉素对外周血淋巴细胞的影响。","authors":"H Blomgren, F Edsmyr, I Näslund","doi":"10.3109/02841867709133953","DOIUrl":null,"url":null,"abstract":"<p><p>Five patients with carcinoma of the penis receiving radiation therapy and injections of Bleomycin were examined to determine whether Bleomycin affects the peripheral pool of lymphoid cells. Total lymphocyte counts were not decreased, but transient reduction of the frequency of thymus-dependent cells occurred in 3 patients. The responses of the lymphocytes to phytomitogens and PPD were temporarily decreased these 3 patients. In 2 subjects the phytomitogen reactivity of the lymphocytes was improved after treatment.</p>","PeriodicalId":7139,"journal":{"name":"Acta radiologica: therapy, physics, biology","volume":"16 4","pages":"325-36"},"PeriodicalIF":0.0000,"publicationDate":"1977-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/02841867709133953","citationCount":"5","resultStr":"{\"title\":\"Effect of bleomycin on peripheral lymphocytes.\",\"authors\":\"H Blomgren, F Edsmyr, I Näslund\",\"doi\":\"10.3109/02841867709133953\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Five patients with carcinoma of the penis receiving radiation therapy and injections of Bleomycin were examined to determine whether Bleomycin affects the peripheral pool of lymphoid cells. Total lymphocyte counts were not decreased, but transient reduction of the frequency of thymus-dependent cells occurred in 3 patients. The responses of the lymphocytes to phytomitogens and PPD were temporarily decreased these 3 patients. In 2 subjects the phytomitogen reactivity of the lymphocytes was improved after treatment.</p>\",\"PeriodicalId\":7139,\"journal\":{\"name\":\"Acta radiologica: therapy, physics, biology\",\"volume\":\"16 4\",\"pages\":\"325-36\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1977-08-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.3109/02841867709133953\",\"citationCount\":\"5\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Acta radiologica: therapy, physics, biology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.3109/02841867709133953\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Acta radiologica: therapy, physics, biology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3109/02841867709133953","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Five patients with carcinoma of the penis receiving radiation therapy and injections of Bleomycin were examined to determine whether Bleomycin affects the peripheral pool of lymphoid cells. Total lymphocyte counts were not decreased, but transient reduction of the frequency of thymus-dependent cells occurred in 3 patients. The responses of the lymphocytes to phytomitogens and PPD were temporarily decreased these 3 patients. In 2 subjects the phytomitogen reactivity of the lymphocytes was improved after treatment.
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