乙醛对心肌超微结构功能的影响。

Recent advances in studies on cardiac structure and metabolism Pub Date : 1976-05-26

W G Nayler, E Fassold

{"title":"乙醛对心肌超微结构功能的影响。","authors":"W G Nayler, E Fassold","doi":"","DOIUrl":null,"url":null,"abstract":"The effect of acetaldehyde, the hepatic metabolite of alcohol, on the functioning of cardiac muscle was investigated at the subcellular level. Concentrations of acetaldehyde that occur in plasma failed to alter either the microsomal Ca2+-accumulating and ATPase activity or the Ca2+-accumulating activity of the mitochondria. These same concentrations of acetaldehyde inhibited the Ca2+-dependent myofibrillar ATPase.","PeriodicalId":21025,"journal":{"name":"Recent advances in studies on cardiac structure and metabolism","volume":"11 ","pages":"489-94"},"PeriodicalIF":0.0000,"publicationDate":"1976-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Effect of acetaldehyde on functioning of cardiac muscle at the ultrastructural level.\",\"authors\":\"W G Nayler, E Fassold\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The effect of acetaldehyde, the hepatic metabolite of alcohol, on the functioning of cardiac muscle was investigated at the subcellular level. Concentrations of acetaldehyde that occur in plasma failed to alter either the microsomal Ca2+-accumulating and ATPase activity or the Ca2+-accumulating activity of the mitochondria. These same concentrations of acetaldehyde inhibited the Ca2+-dependent myofibrillar ATPase.\",\"PeriodicalId\":21025,\"journal\":{\"name\":\"Recent advances in studies on cardiac structure and metabolism\",\"volume\":\"11 \",\"pages\":\"489-94\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1976-05-26\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Recent advances in studies on cardiac structure and metabolism\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Recent advances in studies on cardiac structure and metabolism","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 0

摘要

在亚细胞水平上研究了酒精的肝脏代谢物乙醛对心肌功能的影响。血浆中出现的乙醛浓度不能改变微粒体Ca2+积累和atp酶活性，也不能改变线粒体Ca2+积累活性。这些相同浓度的乙醛抑制Ca2+依赖性肌纤维atp酶。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

微信好友朋友圈 QQ好友复制链接

本刊更多论文

Effect of acetaldehyde on functioning of cardiac muscle at the ultrastructural level.

The effect of acetaldehyde, the hepatic metabolite of alcohol, on the functioning of cardiac muscle was investigated at the subcellular level. Concentrations of acetaldehyde that occur in plasma failed to alter either the microsomal Ca2+-accumulating and ATPase activity or the Ca2+-accumulating activity of the mitochondria. These same concentrations of acetaldehyde inhibited the Ca2+-dependent myofibrillar ATPase.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Recent advances in studies on cardiac structure and metabolism

自引率

0.00%

发文量