基于患者病史的神经网络深度学习肝炎预测分析模型

J. Pîzarro, Byron Vásquez, Willan Steven Mendieta Molina, Remigio Hurtado
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摘要

首先,人工智能的应用之一是疾病的预测,包括肝炎。肝炎多年来一直是一种复发性疾病,因为它严重影响人口,每年死亡人数增加125 000人。这种炎症和器官损伤的过程会影响它的功能,也会影响身体其他器官的功能。在这项工作中,分析了变量及其对目标变量的影响,并从预测模型中给出了结果。我们提出了一种结合人工神经网络的预测分析模型,并将这种预测方法与其他面向分类的模型(如支持向量机(SVM)和遗传算法)进行了比较。我们把我们的方法作为一个分类问题来处理。这种方法需要事先进行数据处理和探索性分析,以确定直接影响这类疾病的变量或因素。通过这种方式,我们将能够确定干预这种疾病发展的变量,影响肝脏或该器官的正常功能,给人体带来不适,以及肝功能衰竭或肝癌等并发症。我们的模型分为以下几个步骤:首先,执行数据提取,这些数据是从加州大学欧文分校(UCI)的机器学习存储库中收集的。然后这些数据经过一个变量转换过程。然后通过神经网络对其进行学习和优化处理。优化(微调)分三个阶段进行:复杂度超参数优化、神经网络层密度优化和dropout正则化优化。最后,对结果进行可视化分析。我们使用了一组患者病历数据,其中的变量有:年龄、性别、性别、血红蛋白等。我们已经发现了与这种疾病间接或直接相关的因素。根据召回率(Recall)、精确率(Precision)和MAE三个质量指标给出了模型的结果。我们可以说,这项研究为新的挑战敞开了大门,例如医学领域的新实现,不仅专注于肝脏,而且能够将开发环境扩展到人体的其他应用和器官,以避免可能的风险,或未来的并发症。应该指出的是,未来使用人工神经网络的应用正在不断发展,改进模型的应用,如使用随机森林、装配算法,在生物医学工程和重点领域都显示出巨大的应用能力,可以分析不同类型的医学图像。
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Hepatitis predictive analysis model through deep learning using neural networks based on patient history
First of all, one of the applications of artificial intelligence is the prediction of diseases, including hepatitis. Hepatitis has been a recurring disease over the years as it seriously affects the population, increasing by 125,000 deaths per year. This process of inflammation and damage to the organ affects its performance, as well as the functioning of the other organs in the body. In this work, an analysis of variables and their influence on the objective variable is made, in addition, results are presented from a predictive model.We propose a predictive analysis model that incorporates artificial neural networks and we have compared this prediction method with other classification-oriented models such as support vector machines (SVM) and genetic algorithms. We have conducted our method as a classification problem. This method requires a prior process of data processing and exploratory analysis to identify the variables or factors that directly influence this type of disease. In this way, we will be able to identify the variables that intervene in the development of this disease and that affect the liver or the correct functioning of this organ, presenting discomfort to the human body, as well as complications such as liver failure or liver cancer. Our model is structured in the following steps: first, data extraction is performed, which was collected from the machine learning repository of the University of California at Irvine (UCI). Then these data go through a variable transformation process. Subsequently, it is processed with learning and optimization through a neural network. The optimization (fine-tuning) is performed in three phases: complication hyperparameter optimization, neural network layer density optimization, and finally dropout regularization optimization. Finally, the visualization and analysis of results is carried out. We have used a data set of patient medical records, among the variables are: age, sex, gender, hemoglobin, etc. We have found factors related either indirectly or directly to the disease. The results of the model are presented according to the quality measures: Recall, Precision and MAE.We can say that this research leaves the doors open to new challenges such as new implementations within the field of medicine, not only focused on the liver, but also being able to extend the development environment to other applications and organs of the human body in order to avoid risks possible, or future complications. It should be noted that the future of applications with the use of artificial neural networks is constantly evolving, the application of improved models such as the use of random forests, assembly algorithms show a great capacity for application both in biomedical engineering and in focused areas to the analysis of different types of medical images.
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