在黎巴嫩市场零售的一些食品零食的致突变性筛选

Espérance Debs, F. Saad, F. Dabboussi
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引用次数: 1

摘要

黎巴嫩市场上零售的一些食品零食的致突变性筛选食品添加剂的使用越来越频繁。可能在膳食产品中,特别是在食品零食中掺入基因毒性化学物质,迫切需要对其进行评估。采用突变色板法对黎巴嫩市场零售的127份食品零食样品进行鼠伤寒沙门菌TA98和TA100诱变活性筛选。食品项目分为两类:第一类符合国际认可的高标准;第二类是成本较低但质量一般较差的。第一类被发现即使在外源S9-混合物激活后也没有诱变活性。然而,35.8%的第二类样品显示突变性,显着性为99%,尽管没有代谢激活。这些令人震惊的结果表明,应采取严厉措施,以保护黎巴嫩消费者免受这种饮食来源引起的潜在诱变风险。
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Screening of Mutagenicity of Some Food Snacks Retailed on the Lebanese Market
Screening of Mutagenicity of Some Food Snacks Retailed on the Lebanese Market Usage of food additives has become more and more frequent. Possible incorporation of genotoxic chemicals in dietary products, especially in food snacks, urges the need for their assessment. A total of 127 samples of food snacks, retailed on the Lebanese market, were screened for mutagenic activity towards Salmonella typhimurium strains TA98 and TA100 using Muta-ChromoPlate assay. The food items fall into two separate categories: the first category abides by high standards internationally approved; the second category is of a lower cost and a general poor quality. The first category was found to show no mutagenic activity even after exogenous S9- mix activation. However, 35.8% of the second category samples exhibited mutagenicity at 99% of significance, although without metabolic activation. These alarming results imply that drastic measures should be undertaken in order to protect the Lebanese consumers from being exposed to a potential risk of mutagenicity induced by such a dietary source.
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