酸橙皮提取物漱口水作为一种非药物制剂抑制龋齿细菌的潜力

E. L., Supriyana Supriyana, Lanny Sunarjo
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引用次数: 1

摘要

龋齿是一种牙齿硬组织的疾病,它会攻击牙釉质、牙本质和牙骨质,其特征是牙齿硬组织的脱矿。变形链球菌本身就是一种存在于口腔内的细菌。由于牙齿表面的细菌在清除矿物质的过程中引起的传染病之一被称为龋齿。另一种解决抑制龋齿细菌问题的方法是使用草药漱口水。其中之一是酸橙皮。酸橙皮具有抑制变形链球菌细菌的潜力,如形成一个抑制带所示,这是对变形链球菌细菌形成的。制备一种可行且有效抑制变形链球菌生长的酸橙皮提取物漱口水制剂。本研究为纯后测对照组设计的真正实验。之所以选择这种设计,是因为它被分为治疗组和对照组。干预组采用浓度分别为15%、25%和50%的酸橙皮提取物漱口水,对照组采用UNISSULA医学院生物医学实验室漱口水配方。从24小时内的平均抑制图来看,柠檬皮提取物漱口水浓度最低为15% = 8.83 mm,最高抑制带为50% = 10.50 mm, 25%浓度= 9.80 mm,对照组为药学院UNISSULA配方漱口水生物医学实验室合剂= 10,13 mm。酸橙皮提取物漱口水对抑制引起龋齿的变形链球菌是可行和有效的。
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The Potential of Lime Peel Extract Mouthwash as A Non-Pharmacological Preparation Inhibits Caries Bacteria
Dental caries is a disease of the hard tissue of the teeth that attacks the enamel, dentin and cementum which is characterized by the demineralization of the hard tissue of the teeth. Streptococcus mutans bacteria itself is one of the bacteria found and lives in the oral cavity. One of the infectious diseases caused by the process of removing minerals due to bacteria on the surface of the teeth is called caries. An alternative choice as an effort to solve the problem of inhibiting caries-causing bacteria is by using herbal mouthwash. One of them is lime peel. Lime peel has the potential to inhibit Streptococcus mutans bacteria as indicated by the formation of an inhibition zone, which is formed against Streptococcus mutans bacteria. Making a mouthwash preparation of lime peel extract (Citrus Aurantifolia) which is feasible and effective in inhibiting the growth of Streptococcus mutans bacteria. This research is a true experiment with post test only control group design. This design was chosen because it was grouped into treatment and control groups. The intervention was given in the form of lime peel extract mouthwash with concentrations of 15%, 25% and 50%, while the administration of the UNISSULA Faculty of Medicine Biomedical Laboratory Mouthwash Formula was the control group. Based on the average inhibition graph within 24 hours, the concentration of extract mouthwash The lowest lime peel was 15% = 8.83 mm, the highest inhibition zone was at a concentration of 50% = 10.50 mm, 25% concentration = 9.80 mm, the control group Formula Mouthwash Biomedical Laboratory Concoction of the Faculty of Medicine UNISSULA = 10, 13mm. Lime peel extract mouthwash is feasible and effective in inhibiting streptococcus mutans which causes caries.
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